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High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/11/6
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Morphological Integration of Soft-Tissue Facial Morphology in Down Syndrome and Siblings
trisomy 21 craniofacial morphology
2014/11/6
Down syndrome (DS), resulting from trisomy of chromosome 21, is the most common live-born human aneuploidy. The phenotypic expression of trisomy 21 produces variable, though characteristic, facial mor...
Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
autocrine signaling bone marrow cells breast cancer
2014/11/6
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Dermoid cysts of the tongue: report of five cases and review of the literature
dermoid cyst lingual
2014/11/6
Dermoid cysts of the tongue are uncommon. To date, there have been nine reported cases in the English language literature. In this article, we describe five cases accessioned at our institution over a...
Evaluation of Cystic Salivary Gland Lesions by Fine-Needle Aspiration: An Analysis of 21 Cases
cystic salivary gland neoplasms fine needle aspiration biopsy
2014/11/6
To analyze the potential sources of diagnostic errors and overall accuracy rate of the fine needle aspiration biopsy (FNAB) diagnosis of cystic salivary gland neoplasms. Study Design: A 10-year (1993-...
Salivary Heterotopia Of The Parathyroid Gland: A Report of Two Cases and Review of the Literature
salivary gland parathyroid
2014/11/6
Two cases of periparathyroid salivary gland heterotopia are described. A review of the records of the Department of Pathology, Long Island Jewish Medical Center, over a 4-year period, identified 759 s...
C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma
c-kit expression salivary gland neoplasms
2014/11/6
Objective. Differentiating between adenoid cystic carcinomas (ACCs), polymorphous low-grade adenocarcinomas (PLGAs), and the monomorphic adenomas (including canalicular adenomas, trabecular adenomas, ...
Gene-enhanced tissue engineering for dental hard tissue regeneration: (I) dentin-pulp and periodontal regeneration
tissue engineering tissue regeneration gene-based therapy
2014/11/6
Gene-based therapies for tissue regeneration involve delivering a specific gene to a target tissue with the goal of changing the phenotype or protein expression profile of the recipient cell; the ulti...
Dynamin Forms a Src Kinase–sensitive Complex with Cbl and Regulates Podosomes and Osteoclast Activity
dynamin osteoclast activity
2014/11/6
Podosomes are highly dynamic actin-containing adhesion structures found in osteoclasts, macrophages, and Rous sarcoma virus (RSV)-transformed fibroblasts. After integrin engagement, Pyk2 recruits Src ...
Signaling via the Pyk2-Src-Cbl complex downstream of integrins contributes to the assembly, organization, and dynamics of podosomes, which are the transient adhesion complexes of highly motile cells s...
Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas
p63 adenoid cystic carcinoma
2014/11/6
Purpose The purpose of this study was to determine the extent of p63 immunoreactivity in the malignant salivary gland neoplasms adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma...
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice
podosome organization bone density osteoclast functions
2014/11/6
The protein tyrosine kinase Pyk2 is highly expressed in osteoclasts, where it is primarily localized in podosomes. Deletion of Pyk2 in mice leads to mild osteopetrosis due to impairment in osteoclast ...
Review of long-term adverse effects associated with the use of chemically-modified animal and nonanimal source hyaluronic acid dermal fillers
hyaluronic acid Restylane® Hylaform® injectable dermal filler granuloma foreign body reaction
2014/11/6
Although only recently introduced, chemically-modified hyaluronic acid dermal fillers have gained widespread acceptance as “rede- fining” dermal fillers in the fields of dermatology and cosmetic facia...
感染根管中产黑色素杆菌检测率的影响因素
产黑色素杆菌 感染根管 检测率
2014/3/18
产黑色素杆菌与感染根管密切相关，但各项研究得出的检测率存在一定差异。本文通过对国内外诸多文献中的试验数据进行比较，分析了影响感染根管中产黑色素杆菌检测率的主要因素，其中包括样本量、样本来源地区、取样部位、患者的临床症状和检测方法，希望将来能通过控制影响因素更全面地评价该细菌在根尖周感染中所占的地位。