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Rare events and stochastic tunneling in a two-locus system with recombination
Rare events stochastic tunneling two-locus system
2011/1/5
We study the evolution of a population in a two-locus genotype space, in which the negative effects of two single mutations are overcompensated in a high fitness double mutant. We discuss how the inte...
A Network-Based Meta-Population Approach to Model Rift Valley Fever Epidemics
Network-Based Meta-Population Rift Valley Fever Epidemics
2011/1/5
Rift Valley Fever virus (RVFv) has been expanding its geographical distribution with important implications for both human and animal health. The emergence of Rift Valley Fever (RVF) in the Middle Eas...
Robust entrainment of circadian oscillators requires specific phase response curves
Robust entrainment circadian oscillators
2011/1/5
The circadian clocks keeping time of day in many living organisms rely on self-sustained biochemical oscillations which can be entrained by external cues, such as light, to the 24-hour cycle induced b...
A network observed in a particular context may appear to have "unusual" properties. To quantify this, it is appropriate to randomize the network and test the hypothesis that the network is not statist...
We introduce a dengue model (SEIR) where the human individuals are treated on an individual basis (IBM) while the mosquito population, produced by an independent model, is treated by compartments (SEI...
In the small phylogeny problem we, are given a phylogenetic tree and gene orders of the extant species and our goal is to reconstruct all of the ancestral genomes so that the number of evolutionary op...
Flows in complex biochemical networks: Role of low degree nodes
Flows complex biochemical networks low degree nodes
2011/1/5
Metabolic networks have two properties that are generally regarded as unrelated: One, they have metabolic reactions whose single knockout is lethal for the organism, and two, they have correlated sets...
Quantification and Minimization of Crosstalk Sensitivity in Networks
Quantification Minimization Crosstalk Sensitivity
2011/1/5
Crosstalk is defined as the set of unwanted interactions among the different entities of a network. Crosstalk is present in various degrees in every system where information is transmitted through a m...
Asymptotic and bifurcation analysis of wave-pinning in a reaction-diffusion model for cell polarization
Asymptotic bifurcation analysis wave-pinning reaction-diffusion model
2011/1/5
We describe and analyze a bistable reaction-diffusion (RD) model for two interconverting chemical species that exhibits a phenomenon of wave-pinning: a wave of activation of one of the species is init...
Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
Dynamics Bacteriophage Genome Ejection Vitro Vivo
2011/1/5
Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires subst...
Conan is a C++ library created for the accurate and efficient modelling, inference and analysis of complex networks. It implements the generation and modification of graphs according to several publis...
We study in this paper certain properties of the responses of dynamical systems to external inputs. The motivation arises from molecular systems biology. and, in particular, the recent discovery of an...
A statistical method for revealing form-function relations in biological networks
statistical method revealing form-function relations biological networks
2011/1/5
Over the past decade, a number of researchers in systems biology have sought to relate the function of biological systems to their network-level descriptions -- lists of the most important players and...
曼氏无针乌贼胚胎发育形态及发育时序的研究
曼氏无针乌贼 胚胎发育 形态描述 参数测量
2012/9/25
观察了室内培育的曼氏无针乌贼自然生产的受精卵形态和胚胎发育过程. 结果表明, 曼氏无针乌贼受精卵成乳头状, 平均卵长 10 mm, 平均卵宽5.5 mm, 受精卵外被黑色坚韧而富有弹性的三级卵膜, 成串聚集一起成葡萄状. 胚胎发育分为12 个阶段: 受精卵期、卵裂期、囊胚期、原肠胚期、初具形态期、腕分化期、心跳出现期、色素出现期、内骨骼形成期、尾腺出现期、缘膜形成期、孵化期. 其胚...