搜索结果: 46-60 共查到“知识库 酶学”相关记录721条 . 查询时间(5.987 秒)
SO2和BAaP复合暴露诱导小鼠心脏线粒体损伤的分子机制初探
细胞色素C氧化酶 合酶
2015/8/10
采用 Ｃ５７ＢＬ６ 小鼠作为模型，ＳＯ２（７ ｍｇ·ｍ
－３
）动式吸入染毒 ２８ ｄ，每天染毒 ６ ｈ；ＳＯ２吸入染毒开始后的第 １～５ ｄ，每天在 ＳＯ２吸入染毒结束
后对小鼠进行腹腔注射 ＢａＰ（４０ ｍｇ·ｋｇ
－１
（ｂ．ｗ．）），１ ｄ 注射 １ 次．吸入染毒结束后，采用荧光定量 ＰＣＲ 技术检测小鼠心肌细胞中由核 ＤＮＡ
（ｎＤＮＡ）编码的细胞色素 Ｃ 氧化酶亚基 ＣＯ４...
DISTINCT LOCALIZATION OF NADPH OXIDASE FLAVOCYTOCHROME B IN RESTING AND INTERFERON GAMMA ACTIVATED MACROPHAGES
Host defense superoxide
2015/5/21
Flavocytochrome b558, the catalytic core of the phagocytic NADPH oxidase, mediates the transfer of electrons from NADPH to molecular oxygen to generate superoxide for host defense. Flavocytochrome b i...
The individual and combined effects of exercise and collagenase on the rodent Achilles tendon
animal models endinopathy
2015/5/21
Tendinopathy is a common degenerative pathology that is characterized by activity related pain, focal tendon tenderness, intratendinous imaging changes, and typically results in changes in the histolo...
Analysis of the Spatiotemporal Localization of Mitochondrial DNA Polymerases of Trypanosoma brucei
cell cycle DNA polymerase kinetoplast DNA microscopy mitochondrion Trypanosomes
2015/1/28
The mitochondrion contains its own genome. Replication of the mitochondrial DNA (mtDNA) is an essential process that, in most organisms, occurs through the cell cycle with no known mechanism to ensure...
Effect of vitamin E and selenium on blood glutathione peroxidase activity and some immunological parameters in sheep
sheep glutathione preoxidase
2015/1/20
The objective of this study was to determine the effect of vitamin E and selenium administration on glutathione peroxidase (GSH-Px) activity and selected parameters of cellular immunity (metabolic act...
本文论述了微生物细胞内磷酸盐转运机制和与聚磷相关的酶—PPK、 PPX及两者对微生物聚磷行为的调控,并对今后研究重点做出展望.论文认为对于微生物聚磷的研究应从纯种微生物转移到强化生物除磷系统的混合微生物菌群,运用分子生物学和生物信息学手段分析聚磷优势菌种的PPK和PPX酶的结构特征及其在活性污泥中的变化规律,进一步深入认识生物除磷调控机理,开辟寻求提高系统除磷效率的新途径.
Discovery of Novel Regulators of Aldehyde Dehydrogenase Isoenzymes
Aldehyde dehydrogenase high-throughput screening computational docking
2015/1/7
Over the past three years we have been involved in high-throughput screening in an effort to discover novel small molecular modulators of aldehyde dehydrogenase (ALDH) activity. In particular, we have...
Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells
telomerase BRCA breast cancer telomeres
2015/5/21
Telomere maintenance is a critical component of genomic stability. An increasing body of evidence suggests BRCA1, a tumor suppressor gene with a variety of functions including DNA repair and cell cycl...
生物计算机时代即将来临
生物计算机 非枚举型DNA计算机 并行型DNA计算机 大规模型DNA计算机 密码分析与破译 研究进展 发展建议
2014/2/18
生物计算机是以核酸分子作为“数据”，以生物酶及生物操作作为信息处理工具的一种新颖的计算机模型。生物计算的早期构想始于1959 年，诺贝尔奖获得者Feynman 提出利用分子尺度研制计算机；1994 年，图灵奖获得者Adleman 提出基于生化反应机理的DNA计算模型；在生物计算机方面突破性工作是北京大学在2007 年提出的并行型DNA计算模型，将具有61 个顶点的一个3-色图的所有48 个3-着色...
Preliminary Comparative Physiological and Biochemical Study of Five Different Goat Breeds Inhabiting Saudi Arabia
Goat Breeds Electrophoresis Isoenzymes Physiology Saudi Arabia
2013/3/8
Three arbitrary chosen enzymes were examined by native-polyacrylamide gel electrophoresis to investigate physiological and genetic variations among five different goat breeds inhabiting Saudi Arabia. ...
Tissue-Specific Isoenzyme Variations in Tilapia Fish, Oreochromis niloticus
Oreochromis niloticus Malate Dehydrogenase Acid Phosphatase Peroxidase Isoenzymes
2013/3/8
Native polyacrylamide gel electrophoresis have been used to analyze malate dehydrogenase (MDH), acid phosphatase (Acph) and peroxidase (Px) isoenzymes in different tissues (liver, kidney, muscle and h...
Single-enzyme analysis in a droplet-based micro-and nanofluidic system
Single-enzyme analysis droplet micro nanofluidic system
2016/12/2
The kinetic activity of individual enzyme molecules was determined in aqueous droplets generated in a nano- and microfluidic device. To avoid high background noise, the enzyme and substrate solution w...
Production, Purification and Characterization of Inulinase from a Newly Isolated Streptomyces sp. CP01
Characterization Inulinase Production Purification Streptomyces
2013/3/8
Inulinase is an enzyme catalyzing the hydrolysis of inulin, a plant reserve polysaccharide, into fructoses and fructooligosaccharides which are widely used as food additives. Here we report inulinase ...