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How, and for what purpose, are cities and populations tracked, virtualized, and simulated by computational infrastructures in realtime? The semester's second Preston Thomas Memorial Symposium — "Real ...
Mice have long been a central part of neuroscience research, providing a flexible model that scientists can control and study to learn more about the intricate inner workings of the brain. Historicall...
当光线进入眼睛时,我们大脑视觉区域的神经元开始放电。然而,大脑适应这种长时间的输入是因为神经元疲劳,还是为了增强感知能力而更有选择性地放电?长期以来,该领域存在两个不同的假说。
表观转录组被发现参与调控包括RNA转录、剪切、转运、翻译、稳定性、降解、折叠等各个方面的RNA代谢过程,调节发育、衰老以及肿瘤发生等多种生物学过程。多项研究发现,表观转录组在哺乳动物神经系统中发挥了多种多样的调控作用,但研究主要集中在mRNA的N6-腺苷酸甲基化(m6A)修饰上,其他类型的RNA化学修饰功能尚待研究。近日,美国宾夕法尼亚大学在《Cell Stem Cell》发表题为“Epitran...
The brain’s cerebral cortex produces perception based on the sensory information it’s fed through a region called the thalamus.
People who share a political ideology have more similar ‘neural fingerprints’ of political words and process new information in similar ways, according to a new analysis led by Brown University resear...
病原微生物或寄生虫侵袭可改变宿主动物的社会性行为,如交配、聚集、侵略、交流等。信息素作为大多数生物感知外界环境、调节社会性行为的重要小分子物质,其在病原微生物改变宿主社会性行为中作用一直是领域内的研究热点。
神经胶质细胞不仅可以支持和连接不同神经元,还起着分配营养物质、参与修复和吞噬过程等重要作用,但神经胶质细胞的亚群类型和分子特性仍有待深入了解。美国宾夕法尼亚大学的研究团队绘制了人类多种神经胶质细胞各阶段分子图谱,相关成果在《Cell Stem Cell》发表,论文的标题为:A single-cell transcriptome atlas of glial diversity in the hum...
Nearly 20 years ago, scientists developed ways to stimulate or silence neurons by shining light on them. This technique, known as optogenetics, allows researchers to discover the functions of specific...
What a long, strange trip it’s been for psychedelic drugs. From their use in ancient indigenous ceremonies, to their often-caricatured association with the 1960s counterculture, to their recent reemer...
One of neuroscience’s greatest challenges is to bridge the gaps between the external environment, the brain’s internal electrical activity, and the abstract workings of behavior and cognition. Many ne...
The study is an example of how brain imaging technology — in this case developed by researchers at Brown University — can be adapted to advance knowledge of brain processes and prompt new questions ab...
The nervous system works because neurons communicate across connections called synapses. They “talk” when calcium ions flow through channels into “active zones” that are loaded with vesicles carrying ...
越来越多的证据记录了2019年冠状病毒病(COVID-19)感染尤其是重症感染引发的神经系统并发症,包括脑血管后遗症、精神分裂症和抑郁症等。鉴于COVID-19大流行的规模,可以预见,数量惊人的COVID-19幸存者可能会面临感染导致的终生神经精神疾病后遗症。冠状病毒对大脑的攻击是多方面的,因此,研究SARS-COV-2感染对神经系统影响的分子机制及愈后康复非常重要。
It was late on a Saturday night and snowing hard when doctoral students Rose Tatarsky and Najva Akbari emerged from a basement laboratory in Clark Hall, giddy with a sense of discovery.

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