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The WRKY transcription factor (TF) belongs to one of the major plant protein superfamilies. The WRKY TF gene family plays an important role in the regulation of transcriptional reprogramming associate...
Two signal molecules, salicylic acid (SA) and N-hydroxypipecolic acid (NHP), play critical roles in plant immunity. The biosynthetic genes of both compounds are positively regulated by master immune-r...
The appropriate timing of flowering is critical for plant reproductive success. Although the FLOWERING LOCUS T (FT)-FD module plays crucial roles in the photoperiodic flowering pathway, the underlying...
FOXP transcription factors play important roles in neurodevelopment, but little is known about how their transcriptional activity is regulated. FOXP proteins cooperatively regulate gene expression by ...
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear transcription factors that belong to the steroid receptor superfamily. This family of PPARs includes PPARa, PPARd, PPARg1...
Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
CD4 Silencing in Thmocytes is Opposed by the Enforced Association of P300 HAT, HDAC1 or SUV39H1 with Runx Transcription Factors.
Cytokines are extracellular proteins that mediate communication between cells. T helper cell subsets secrete specific cytokines that promote the development of inflammation. Naïve CD4+ T cells ac...
By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activ...
Gene specific regulation of transcription is of fundamental importance to cell survival. When the yeast, Saccharomyces cerevisiae is challenged by growth under conditions of nutrient limitation the ce...
Understanding how genes get turned on or off is central to the study of biological processes in both health and disease. Several regulatory mechanisms, which can be positive or negative, have been...
转录因子在高等植物的生长发育及其对外界环境的反应中起着重要的调控作用。典型的高等植物转录因子含有DNA结合域、转录调控域、寡聚化位点和核定位信号,转录因子通过这些结构域与顺式元件相互作用调控基因的表达。最近的研究表明它们有可能成为人类调控植物生长发育的新型工具。本文综述了高等植物转录因子的结构、转录因子功能的研究方法等最新研究进展,并详细阐述了转录因子在高等植物生长发育和形态建成等方面的生物学功能...

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