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Stem cell factor induces heterotopic accumulation of cells（heterotopia）in the mouse cerebral cortex
Stem cell factor heterotopic accumulation of cells (heterotopia) mouse cerebral cortex
2009/5/8
The stem cell factor (SCF)-c-kit signal transduction pathway plays an important role in the proliferation and migration of neural progenitor cells, but little is known about its function during the ...
Expression of c-KIT and its ligand, stem cell factor, in normal and subfertile human testicular tissue
Germ cells proto-oncogenes testis stem cells
2009/2/16
The c-KIT proto-oncogene encodes for a transmembrane receptor and is associated with maturation of several cell types, including germ cells. The ligand of the receptor has been identified as stem ...
Transmembrane versus soluble stem cell factor expression in human testis
Transmembrane soluble stem cell human testis
2008/12/25
The interaction between stem cell factor (SCF), a ligand produced by Sertoli cells, and its c-kit receptor on germ cells is necessary for successful spermatogenesis in animal models. SCF can be alte...
Effects of Th2 cytokines and eosinophils on stem cell factor production by lung fibroblasts
eosinophil fibroblast interleukin-4 interleukin-5 stem cell factor
2010/11/24
Interleukin-4 significantly enhanced SCF production, whereas tumor necrosis factor-α, interferon-γ and IL-1α showed suppressive effects on SCF pro-duction. When fibroblasts were cultured with IL-4 plu...
Mouse bone marrow-derived mast cells acquire responsiveness to substance P after co-culture with 3T3 fibroblasts in the presence of stem cell factor
co-culture mast cells stem cell factor substance P 3T3 fibroblasts
2010/11/29
Connective tissue-type mast cells degranulate in response to a neurogenic peptide, substance P, whereas bone marrow-derived mast cells (BMMC) do not respond to this stimulant when prepared with a comb...