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CATHELICIDIN LL-37, GRANZYMES, TGF-β1 AND CYTOKINES LEVELS IN INDUCED SPUTUM FROM FARMERS WITH AND WITHOUT COPD
cathelicidin LL-37 granzymes TGF-β1 cytokines farmers
2010/12/22
The cathelicidin LL-37 is an antimicrobial and lipopolysaccharide neutralizing peptide, possessing pro-inflammatory, tissue repair and remodeling activities. Recent reports indicate that the progressi...
Quality Control of Sputum Smears Examination by Re-Reading in a Tuberculosis Screening
Double-reading Tuberculosis screening Quality control
2009/12/15
Background: Sputum smear examination is the basis of diagnosis of tuberculosis and quality control for the correct diagnosis of tuberculosis is necessary. This study was a method survey and perfo...
Evaluation of the Efficacy of Five DNA Extraction Methods for the Detection of Mycobacterium tuberculosis DNA in Direct and Processed Sputum by an In-House PCR Method
DNA extraction Mycobacterium tuberculosis PCR
2009/5/20
Aim: DNA extraction is an important step from clinical samples for molecular diagnosis of tuberculosis by PCR. The aim of this study was to evaluate the efficacy of five DNA extraction methods [boil...
Sputum Eosinophilia, Airway Hyperresponsiveness and Airway Narrowing in Young Adults with Former Asthma
airway hyperresponsiveness airway inflammation airway narrowing former asthma remission
2010/11/17
31 subjects were former asthma subjects (FBA), 11 subjects were current asthma subjects (CBA) and 284 subjects had no history of asthma (non-BA). PC20 and FEV1/FVC ratio were significantly lower in th...
Flow cytometric analysis of lymphocytes and lymphocyte subpopulations in induced sputum from patients with asthma
bronchial asthma CD4-positive lymphocyte flow cytometry induced sputum interleukin-2 receptor
2010/11/25
Study objectives were to compare the numbers of lymphocytes and lymphocyte subpopulations in induced sputum from asthmatic patients and from healthy subjects, and to determine the effect of inhaled an...
Sulfidopeptide leukotrienes, but not thromboxane B2 or histamine, are elevated in sputum during exacerbation of asthma
asthma histamine sputum sulfidopeptide leukotrienes thromboxane B2
2010/11/25
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...