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南京农业大学农学院《The Plant Cell》在线发表万建民院士团队“A CYP78As–SMG4–COPⅡpathway promotes grain size in rice”（图）
万建民 基因资源 细胞定位
2023/10/28
2023年9月25日，万建民院士团队在The Plant Cell在线发表了题为“A CYP78As–SMG4–COPⅡpathway promotes grain size in rice”的研究论文。该团队在水稻中鉴定到一个调控水稻籽粒大小的关键因子SMG4，并阐明其分子机制，为水稻粒型改良提供了新的基因资源。
Five Rice Seed-Specific NF-YC Genes Redundantly Regulate Grain Quality and Seed Germination via Interfering Gibberellin Pathway
NF-YCs 种子发育 赤霉素 籽粒品质
2023/3/9
NF-YCs are important transcription factors with diverse functions in the plant kingdoms including seed development. NF-YC8, 9, 10, 11 and 12 are close homologs with similar seed-specific expression pa...
南京农业大学农学院《Plant Physiology》发表万建民院士团队“Phytochrome B mediates dim-light-reduced insect resistance by promoting the ethylene pathway in rice”（图）
万建民 水稻褐飞虱 基因
2023/10/28
褐飞虱是水稻生产中最严重的害虫。褐飞虱通过针状口器刺入水稻叶鞘组织吸食韧皮部汁液，造成水稻严重减产甚至绝收。种植抗性品种是综合防控褐飞虱的基础。然而植物抗病虫性通常受光照、温度和湿度等环境因素的影响，在一定程度上制约了抗性基因的有效利用。如采用密植的栽培方式是当前许多作物增加单位面积产量的重要途径，但是密植通常会导致冠层以下的植株部分光照不足而产生庇荫反应，易滋生各类病虫害，虽然这种现象普遍存在，...
High-resolution temporal dynamic transcriptome landscape reveals a GhCAL-mediated flowering regulatory pathway in cotton (Gossypium hirsutum L.)
棉花开花 相关基因 GhCAL
2024/5/17
本研究利用不同熟性的棉花高分辨率时间动态转录组，鉴定到棉花开花相关基因GhCAL，并对其介导的棉花开花调节途径进行了解析。研究发现GhCAL基因沉默的转基因棉花植株花芽分化和开花时间显著延迟，GhCAL能够与GhAP1-A04/GhAGL6-D09形成异源二聚体，同时调节GhAP1-A04和GhAGL6-D09的表达。GhAP1-A04和GhAGL6-D09沉默的棉花植株也表现出明显的开花延迟。因...
NAC transcription factor ONAC066 positively regulates disease resistance by suppressing the ABA signaling pathway in rice
NACs ABA ONAC066 SA JA
2023/4/21
NAC transcription factors have been validated as important regulators in stress responses, but their molecular mechanisms in plant disease resistance are still largely unknown. Here we report that the...
Eggs early in complementary feeding increase choline pathway biomarkers and DHA: a randomized controlled trial in Ecuador
egg nutrition children choline betaine vitamin B-12 docosahexaenoic acid
2018/11/21
Background: Choline status has been associated with stunting among young children. Findings from this study showed that an egg intervention improved linear growth by a length-for-age z score of 0.63.
Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate
soluble fiber fermentation pentadecanoic heptadecanoic liver long-chain fatty acid
2018/11/14
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are consider...
Faulty genomic pathway is linked to schizophrenia developing in utero,study finds
Faulty genomic pathway schizophrenia
2017/3/14
The skin cells of four adults with schizophrenia have provided an unprecedented “window” into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Rese...
2017哮喘 Keystone Symposia（2017 Keystone Symposia on Asthma: From Pathway Biology to Precision Therapeutics）
Asthma Pathway Biology
2017/1/17
The meeting will begin on Sunday, February 12 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 16 with a closing plenary ...
Research Reveals Cancer Pathway to Spreading Through the Body
Cancer Pathway Spreading Body
2016/8/11
Cancer cells need oxygen to survive, as do most other life forms, but scientists had never tracked their search for oxygen in their early growth stages until now — a step toward deeper understanding o...
Correlations of genes expression in PPAR signalling pathway with porcine meat quality traits
genetic markers Real-time PCR IMF Longissimus dorsi muscle pig
2016/8/1
The correlation of expression pattern of candidate genes in PPAR signalling pathway with meat quality traits in Longissimus dorsi muscle of pigs was investigated. Meat quality traits were measured and...
Anatomy and Dynamics of a Ligand-Binding Pathway in Myoglobin:The Roles of Residues 45,60,64 and 68
Humans Carbon Monoxide Myoglobin Recombinant Proteins Ligands Spectrum Analysis Protein Binding Kinetics Mutation Thermodynamics
2016/5/23
In order for diatomic ligands to enter and exit myoglobin, there must be substantial displacements of amino acid side chains from their positions in the static X-ray structure. One pathway, involving ...
The Effects of Glucagon-like Peptide-2 on the Tight Junction and Barrier Function in IPEC-J2 Cells through Phosphatidylinositol 3-kinase–Protein Kinase B–Mammalian Target of Rapamycin Signaling Pathway
Transepithelial Electrical Resistance Phosphatidylinositol 3-Kinase-Akt-mTOR Signaling Pathway
2016/5/20
Glucagon-like peptide-2 (GLP-2) is important for intestinal barrier function and regulation of tight junction (TJ) proteins, but the intracellular mechanisms of action remain undefined. The purpose of...
Discovery of new stem cell pathway indicates route to much higher yields in maize,staple crops
new stem cell pathway much higher yields maize staple crops
2016/5/19
Biologists at Cold Spring Harbor Laboratory (CSHL) have made an important discovery that helps explain how plants regulate the proliferation of their stem cells. The discovery has near-term implicatio...