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NEUROPROTECTIVE STUDIES ON THE MPTP AND SOD1 MOUSE MODELS OF NEURODEGENERATIVE DISEASES
ALS MPTP SOD1 neurodegeneration
2015/5/21
The main, underlying cause of neurodegenerative disease is the progressive loss of neuronal structure or function, whereby central and/or peripheral nervous system circuitry is severely and irreversib...
Enzyme-Linked Immunosorbent Assays with High Sensitivity for Antigen-Specific and Total Murine IgE: A Useful Tool for the Study of Allergies in Mouse Models
allergen-specific IgE blocking reagent enzyme-linked immunosorbent assay
2010/11/16
Enhancer solutions are effective in improving ELISAs for total and antigen-specific murine IgE. Selection of blocking reagents was important to decrease unwanted enhancement of background signals and ...
Genetically defined mouse models of male infertility
Genetically defined mouse models male infertility
2009/2/23
The review has four objectives. The first objective is to summarize our studies of gene mutations that induce infertility in male mice. The second objective is to stress the power of mouse genetics ...
Recent Progress in Biotechnology-based Gene Manipulating Systems to Produce Knock-In/Out Mouse Models
Transgenic Knock In/Out ROSA26 Tetraploid ES Cells Gene Manipulation
2016/4/27
Gene-manipulated mice were discovered for the first time about a quarter century ago. Since then, numerous sophisticated technologies have been developed and applied to answer key questions about the ...
A Proposal Concept of a Polygene Network in Systemic Vasculitis: Lessons from MRL Mouse Models
autoantibody Cd72 collagen disease Fas genetic polymorphism
2010/11/18
In addition to the studies of cellular and molecular events in the pathogenesis of systemic vasculitis, a genome analysis of mouse models may shed some light on the complex clinicopathological manifes...
Effects of neuropeptides in the development of the atopic dermatitis of mouse models
atopic dermatitis calcitonin gene-related peptide neuropeptides olopatadine hydrochloride substance P
2010/11/22
It is suggested that repeated contact allergic dermatitis or mental stress may promote the development and exacerbation of AD and that substance P has a role in this response. In addition, it seems th...
Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
active cutaneous anaphylaxis allergy Enterococcus faecalis eosinophils lactic acid bacteria mouse strains
2010/11/19
Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacteriu...