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Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Hydroxychloroquine less toxic derivative chloroquine effective inhibiting SARS-CoV-2 infection vitro
2020/6/12
The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/2019-nCoV) poses a serious threat to global public health and local econom...
Effects of inhibiting starch branching enzymes on molecular and crystalline structures of starches from endosperm different regions in rice
Crystalline structure Endosperm regional tissue Molecular structure Rice Starch Starch branching enzyme
2023/8/9
Mature endosperm was separated regionally into different parts in three rice cultivars, Te-qing (TQ), Wu-xiang 9915 (WX9915) and Guang-ling-xiang-nuo (GLXN), and their transgenic lines with inhibition...
Lower ω-6/ω-3 Polyunsaturated Fatty Acid Ratios Decrease Fat Deposition by Inhibiting Fat Synthesis in Gosling
ω-6/ω-3 Polyunsaturated Fatty Acid Lipid Metabolism Goose
2016/11/10
The objective of the current study was to investigate the effects of dietary ω-6/ω-3 polyunsaturated fatty acid (PUFA) ratios on lipid metabolism in goslings. One hundred and sixty 21-day-old Yangzhou...
Inhibiting effect of shallow seed burial on grass weed emergence
weed control seedling emergence
2016/2/22
The efficacy of superficial tillage as a sustainable tool to reduce the emergence of Digitaria sanguinalis, Setaria viridis, and Sorghum halepense was evaluated with field experiments. Seeds were buri...
Negative Cross-Resistance of Acetolactate Synthase Inhibitor–Resistant Kochia (Kochia scoparia) to Protoporphyrinogen Oxidase– and Hydroxyphenylpyruvate Dioxygenase–Inhibiting Herbicides
ALS-inhibitor resistance herbicide resistance pleiotropic effect target-site mutation
2015/12/23
This greenhouse experiment examined the response of homozygous susceptible and acetolactate synthase (ALS) inhibitorresistant plants from six Canadian kochia accessions with the Pro197 or Trp574 mutat...
Saflufenacil (Kixor™): Biokinetic Properties and Mechanism of Selectivity of a New Protoporphyrinogen IX Oxidase Inhibiting Herbicide
Herbicide mechanism of selectivity metabolism uptake and translocation
2015/12/21
Saflufenacil (Kixor™) is a new protoporphyrinogen IX oxidase (PPO) inhibiting herbicide for preplant burndown and selective PRE dicot weed control in multiple crops, including corn. The biokinet...
Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained,eugonadal males
eight weeks aromatase inhibiting nutritional supplement 6-OXO serum hormone profiles clinical safety markers resistance-trained,eugonadal males
2015/7/13
The purpose of this study was to determine the effects of 6-OXO, a purported nutritional aromatase inhibitor, in a dose dependent manner on body composition, serum hormone levels, and clinical safety ...
Effects of inhibiting nitric oxide synthase on cumulus expansion and nuclear maturation of sheep oocytes
sheep oocyte maturation nitric oxide L-NAME
2015/6/9
Nitric oxide (NO) is a biological signaling molecule that plays a crucial role in oocyte maturation of mammalians. It is generated by the nitric oxide synthase (NOS) enzyme from l-arginine. Although t...
Inhibiting protein clearance to induce cell death in tuberous sclerosis and pancreatic cancer
Ral 4-phenylbutyric acid 4-PBA
2015/5/25
Sequestration at the aggresome and degradation through autophagy are two approaches by which a cell can counteract the toxic effect of misfolded proteins. Tuberous sclerosis (TS) and cancer cells can ...
Bean Polygalacturonase-inhibiting Protein Expressed in Transgenic Brassica napus Inhibits Polygalacturonase from its Fungal Pathogen Rhizoctonia solani
canola bean transformation PGIP
2015/3/9
Polygalacturonase-inhibiting proteins (PGIPs) selectively inhibit polygalacturonases (PGs) secreted by invading plant pathogenic fungi. The objective of present research was to clone and introduce the...
The active site chemistry of factor inhibiting HIF-1, coordination, bonding, and reaction
Pure sciences Autohydroxylation Factor inhibiting HIF Iron center coordination
2014/12/10
Oxygen is vital for aerobic life. A shortage of oxygen can produce disastrous outcomes to cellular functions. To avoid this, eukaryotic cells developed an oxygen sensing machinery of which the key com...
Cloning, characterization, and expression of the gene encoding polygalacturonase- inhibiting proteins from strawberry
Strawberry polygalacturonase-inhibiting proteins (PGIP) cDNA cloning, tissue expression
2010/10/29
Polygalacturonase-inhibiting proteins (PGIP) play important roles in the defense against plant pathogens, especially fungi. The sequence of strawberry PGIP gene was obtained using reverse transcriptio...
Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
airway hyperreactivity asthma prevention Th2 cell tomato extract
2010/11/12
Background: Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes. In this study, we investigated the effect of n...
Elementary Identification of Phenolic Allelochemicals from Dwarf Lilyturf Plant (Ophiopogon japonicus K.) and Their Growth-Inhibiting Effects for Two Weeds in Paddy Rice Field
Allelochemicals Barnyardgrass Dwarf lilyturf HPLC Monchoria
2009/7/29
Dwarf lilyturf (Ophiopogon japonicus K.), used as a weed-suppressing cover crop and a medicinal plant, was suggested to be a promising natural herbicide to control weeds in the rice field through its ...
Hydrostatic pressure reduces synaptic efficiency by inhibiting transmitter release
drug pressure transmitter release
2009/7/16
The amplitude of post-synaptic potentials at an identified synapse in the Aplysia central nervous system can be modulated by the application of hydrostatic pressure. Postsynaptically controlled functi...