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Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
dietary protein protein source high-protein diet gut microbiota
2018/11/19
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for lar...
Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
dietary protein protein source high-protein diet gut microbiota,
2018/11/16
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for lar...
Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial
stroke potassium magnesium enriched salt neurologic performance
2018/11/20
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need. Our previous intervention trial in elderly s...
Probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2) improve rhinoconjunctivitis-specific quality of life in individuals with seasonal allergies: a double-blind, placebo-controlled, randomized trial
healthy adults probiotics seasonal allergies allergic rhinitis quality of life Lactobacillus gasseri Bifidobacterium bifidum Bifidobacterium longum
2018/11/13
Background: Rhinoconjunctivitis-specific quality of life is often reduced during seasonal allergies. The Mini Rhinoconjunctivitis Quality of Life Questionnaire (MRQLQ) is a validated tool used to meas...
Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial
α-carboxyethyl hydroxychromanol α-CEHC α-carboxymethylbutyl
2018/11/13
Background: Vitamin E supplementation improves liver histology in patients with nonalcoholic steatohepatitis, which is a manifestation of the metabolic syndrome (MetS). We reported previously that α-t...
A micronutrient-fortified young-child formula improves the iron and vitamin D status of healthy young European children: a randomized, double-blind controlled trial
iron deficiency vitamin D deficiency cow milk young-child formula vitamin D supplements micronutrient fortification young children
2018/11/12
Background: Iron deficiency (ID) and vitamin D deficiency (VDD) are common among young European children because of low dietary intakes and low compliance to vitamin D supplementation policies. Milk i...
Dual fortification of salt with iodine and microencapsulated iron: a randomized, double-blind, controlled trial in Moroccan schoolchildren
Iodine iron deficiency
2016/12/29
To establish the DFS fortification concentration, we measured salt intake by 3-d weighed food records and estimated iron bioavailability from the local diet by using published algorithms. We then form...
Randomized, double-blind, placebo-controlled clinical trial of choline supplementation in school-aged children with fetal alcohol spectrum disorders
choline clinical trial fetal alcohol spectrum disorders fetal alcohol syndrome nutrition prenatal alcohol exposure supplementation
2018/12/19
Background: Prenatal alcohol exposure results in a broad range of cognitive and behavioral impairments. Because of the long-lasting problems that are associated with fetal alcohol spectrum disorders (...
Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial
NaFeEDTA cognition fortification iron lead
2018/12/18
Background: Lead is a common neurotoxicant and its absorption may be increased in iron deficiency (ID). Thus, iron fortification to prevent ID in populations is a promising lead mitigation strategy. T...
Estimation of the dietary requirement for vitamin D in adolescents aged 14–18 y: a dose-response, double-blind, randomized placebo-controlled trial
adolescents dose-response randomized controlled trial recommendations requirements vitamin D
2018/12/18
Background: Adolescents are a population group at high risk of low vitamin D status, yet the evidence base for establishing dietary vitamin D requirements remains weak.
Double-blind, randomized trial of a synthetic triacylglycerol in formula-fed term infants: effects on stool biochemistry, stool characteristics, and bone mineralization
Term infants full-term infants infant formula
2016/6/2
The low sn-2 palmitate content of infant formulas
results in formation of fatty acid calcium soaps in the stools and
reduced calcium absorption.
Long-term efficacy and safety of a new olive oil–based intravenous fat emulsion in pediatric patients: a double-blind randomized study
Intravenous fat emulsion lipids olive oil
2016/6/1
A new intravenous lipid emulsion (ILE) prepared
from a mixture of soybean and olive oils contains only longchain
triacylglycerols, with a low proportion (20%) of polyunsaturated
fatty acids and 60%...
Acute Garcinia mangostana (mangosteen) supplementation does not alleviate physical fatigue during exercise:a randomized,double-blind,placebocontrolled,crossover trial
α-mangostin Hydroxycitric acid Exercise Exhaustion Muscle dynamic stiffness Blood biochemical
2016/5/16
Background:The purple mangosteen ( Garcinia mangostana), known as the "queen of fruit," is widely consumed and unique not only because of its outstanding appearance and flavor but also its remarkable ...
Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition
amino acid lipid emulsion parenteral nutrition preterm infant randomized controlled trial body composition intrahepatocellular lipid
2018/11/30
Background: Parenteral nutrition is central to the care of very immature infants. Current international recommendations favor higher amino acid intakes and fish oil–containing lipid emulsions.
Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial
magnesium, intervention study, arterial stiffness, pulse wave velocity, blood pressure
2018/11/29
Background: Epidemiologic studies have suggested a protective effect of magnesium intake on cardiovascular disease risk. However, intervention trials of magnesium supplementation on blood pressure and...