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Coenzyme Q: Molecular Mechanisms in Health and Disease
Molecular Mechanisms Health Disease
2016/6/14
New claims about the special health benefits of a particular nutrient
appear in the press almost daily. In the area of trace elements,
2 examples of such claims include the role of zinc lozenges in ...
Estimation of methanogenesis by quantification of coenzyme F430 in marine sediments
methane hydrate methanogens function-specific compound analysis marine sedimen
2017/4/10
Coenzyme F430 is the hydrocorphinoid nickel complex which acts as active site in methyl-coenzyme M reductase
(MCR). The MCR-F430 complex catalyzes the last step of methanogenesis: reduction of methyl...
Coenzyme Q10 Supplementation Modulates NFκB and Nrf2 Pathways in Exercise Training
Coenzyme Q10 exercise signaling pathway
2016/3/11
This study reports the effects of Q10, coenzyme Q10 or ubiquinone, a component of the electron transport chain in mitochondria, on nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB)...
Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth
developmental programming liver disease coenzyme Q low birth weight accelerated postnatal growth
2018/11/28
Background: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmen...
Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals
both trained untrained individuals
2015/7/14
To determine whether acute (single dose) and/or chronic (14-days)
supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by
increasing plasma and muscle CoQ10 concentrat...
Coenzyme Q10 Administration in Community-Acquired Pneumonia in the Elderly
Coenzyme Q10 Elderly Pneumonia
2015/10/16
Background: Community-acquired pneumonia (CAP) is generally considered a major cause of morbidity and mortality in the elderly.
Effects of Coenzyme Q10 Supplementation on Serum Lipoproteins, Plasma Fibrinogen, and Blood Pressure in Patients With Hyperlipidemia and Myocardial Infarction
Myocardial Infarction Coenzyme Q10 Lipoprotein Fibrinogen Blood Pressure
2015/10/15
Background: Low plasma concentrations of coenzyme Q10 (CoQ10) have been associated with concentration of lipoproteins and other factors contributing to coronary heart diseases.
Coenzyme Q10 concentrations in normal and pathological human seminal fluid
eminal fluid sperm count sperm motility ubiquinone varicocele
2009/2/13
Coenzyme Q10 (CoQ10) levels were assayed in total seminal fluid or both in seminal fluid and seminal plasma in 77 subjects with normal or pathological findings at standard semen analysis. CoQ10 leve...
Synthesis of docosahexaenoyl coenzyme A in human spermatozoa
docosahexaenoyl coenzyme A human spermatozoa
2009/2/12
The synthesis of docosahexaenoyl coenzyme A (22:6-CoA) was studied in a long-chain fatty acid: CoASH ligase (AMP)-enriched fraction from human spermatozoa and was compared to palmitoyl CoA (16:0-CoA...
Nourishing and health benefits of coenzyme Q10
coenzyme Q10 ubiquinone food grape wine nourishing nutritional supplement diseases health benefits ageing skin
2014/3/3
Coenzyme Q10 is an important mitochondrial redox component and endogenously produced lipid-soluble antioxidant of the human organism. It plays a crucial role in the generation of cellular energy, enha...
The Expression of Porcine Adiponectin and Stearoyl Coenzyme a Desaturase Genes in Differentiating Adipocytes
Adiponectin Stearoyl Coenzyme A Desaturase Adipose Tissue Pigs
2016/4/15
The gene expression of porcine adiponectin and stearoyl coenzyme A desaturase (SCD) was investigated in this study. The partial gene sequences for adiponectin and SCD were amplified by RT-PCR from sub...
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km):relevance to genetic disease and polymorphisms
Genetic disease therapeutic vitamin use binding defect favism alcohol intolerance autism migraine headaches single nucleotide polymorphisms enzyme mutations review
2016/12/17
As many as one-third of mutations in a gene result in the corresponding enzyme having an increased Michaelis constant, or Km, (decreased binding affinity) for a coenzyme, resulting in a lower rate of ...