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探讨亚洲黄种人炎症性肠病（IBD）患者硫嘌呤甲基转移酶（TPMT）基因多态性与嘌呤类药物不良反应(ADR)之间的关系。方法分别以“thiopurineS-methyltransferase”、“inflammatoryboweldisease/ulcerativecolitis/crohn’sdisease”和“thiopurine/azathioprine/6-mercaptopurine”及“...
Common Cytochrome p4503A (CYP3A4 and CYP3A5) and Thiopurine S-Methyl Transferase (TPMT) Polymorphisms In Turkish Population
pharmacogenetics TPMT CYP3A4 CYP3A5
2009/6/22
Polymorphisms in the genes encoding cytochrome p450 (CYP) and thiopurine S-methyl transferase (TPMT) enzymes catalyze the metabolic reactions of several drugs.These polymorphisms might be responsible ...