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不同生态环境条件下，食物链结构的差异会导致食物链Hg和PUFA在各营养级间传输的变化。作为鱼类的主要食物来源，底栖动物通过食物摄取可将PUFA和Hg由食物链底端传递到高营养级的鱼体。处于低营养级的底栖动物对初级生产者的依赖性更大，更容易受到环境变化的影响。然而，对于Hg和PUFA在水生食物链的积累和传输研究主要集中在鱼类方面，对基础食物链中Hg和PUFA积累机制尚不清楚。
Omega-3 long-chain PUFA intake during pregnancy and allergic disease outcomes in the offspring: a systematic review and meta-analysis of observational studies and randomized controlled trials
allergic disease n–3 LC-PUFA pregnancy allergy prevention fatty acids randomized controlled trial prenatal supplementation asthma eczema hayfever
2018/11/23
Background: There is some evidence that increased maternal intake of omega-3 (n–3) long-chain polyunsaturated fatty acids (LC-PUFAs) during pregnancy may reduce the incidence of immunoglobulin E (IgE)...
Limitations of the review and meta-analysis of fish and PUFA intake and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies
Limitation meta-analysis of fish 21 cohort studies
2018/12/13
The recent meta-analysis by Zhang et al. (1) on fish and PUFA intake and the risk of mild-to-severe cognitive impairment raises several methodologic issues that have important implications for the int...
Can long-chain PUFA supplementation during pregnancy influence later obesity risk?
long-chain PUFA upplementation pregnancy obesity risk
2018/11/30
Epigenetic regulation of adipose tissue by maternal diet during pregnancy could be the next primary prevention strategy to reduce obesity (1). It is well known that human phenotype can be influenced b...
Reduction of the n–6:n–3 long-chain PUFA ratio during pregnancy and lactation on offspring body composition: follow-up results from a randomized controlled trial up to 5 y of age
body composition LCPUFA obesity preschool age prevention
2018/11/30
Background: It has been hypothesized that the n–6:n–3 (ω-6:ω-3) long-chain polyunsaturated fatty acid (LCPUFA) ratio in the maternal diet during the prenatal and early postnatal phase positively affec...
Maternal plasma PUFA concentrations during pregnancy and childhood adiposity: the Generation R Study
adiposity childhood fat mass pregnancy PUFAs
2018/11/28
Background: Maternal polyunsaturated fatty acid (PUFA) concentrations during pregnancy may have persistent effects on growth and adiposity in the offspring. A suboptimal maternal diet during pregnancy...
The effects PCSO-524? a patented marine oil lipid and omega-3 PUFA blend derived from the New Zealand green lipped mussel (Perna canaliculus), on indirect markers of muscle damage and inflammation after muscle damaging exercise in untrained men: a randomized, placebo controlled trial
Omega-3 fatty acids Green-lipped mussel oil blend Muscle damage
2015/7/30
Thirty two untrained male subjects were randomly assigned to consume 1200 mg/d of PCSO- 524?(a green-lipped mussel oil blend) or placebo for 26 d prior to muscle damaging exercise (downhill running), ...
综述了多不饱和脂肪酸( PUFA) 可以抑制脂肪酸合成酶的基因表达, 促进脂肪酸氧化的基因表达的作用。其具体机制可能与3 种
细胞核受体肝细胞核因子-4α( HNF-4α) 、( LXR- α和β) 和过氧化物酶体活化增殖因子受体( PPAR- α,β和γ) 的相互作用以及转录因子胆固醇调节元件结合蛋白( SREBP1 和2) 相关。
随着家禽生产集约化程度提高，养殖密度加大，造成养殖环境恶化。各种环境因子的刺激及传染病的影响，使家禽长期处于应激和免疫失调状态，机体代谢紊乱，从而影响家禽的生产性能和产品品质。如何改善家禽的亚健康或应激状态，充分发挥其生产潜力，成为家禽营养研究的热点之一。多不饱和脂肪酸（PUFA）在人类医学和动物试验研究中被普遍证明具有免疫调节功能，但在家禽生产上的应用研究还处于初级阶段,随着研究的不断深入，多不...
专著信息
书名
Effect of ω-3 PUFA on the proliferation and apoptosis of tumor cells transfected with transmembrane TNFα expression vector containing fatty acid responsive element（abstract）
语种
英文
撰写或编译
作者
Hai...
n-3 PUFA依赖的跨膜型肿瘤坏死因子-α真核表达载体的构建
2007/7/28
期刊信息
篇名
n-3 PUFA依赖的跨膜型肿瘤坏死因子-α真核表达载体的构建
语种
中文
撰写或编译
作者
承海,糜漫天,张乾勇
第一作者单位
刊物名称
第三军医大学学报
页面
27（1），28-30，2005年1月
出版日期
2005年
1月
日
文章标识(ISSN)
相关项目
ω-3脂肪酸可调控的TNFα表达载体的构建及其抗癌效应