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2017神经嵴和颅骨戈登学术会议（The 2017 GRC on Neural Crest & Cranial Placodes）
Neural Crest Cranial Placodes
2017/1/19
This conference uniquely considers two distinct cell types, the neural crest and the cranial placodes, that share evolutionary and embryological origins but have traditionally been studied separately....
Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation
Shp2 pERK Bradycardia
2015/5/25
Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is requir...
Beyond cell Adhesion: Exploring the Role of Cadherin-11 Extracellular Processing by ADAM Metalloproteases in Cranial Neural Crest Migration
ADAM Cadherin Cell migration Cell signaling Cranial neural crest Developmental biology/Embryology
2014/12/10
The migration of the cranial neural crest is an essential part of cranio-facial development in every vertebrate embryo. The cranial neural crest (CNC) is a transient population of cells that forms the...
Molecular Basis and Modification of a Neural Crest Deficit in a Down Syndrome Mouse Model
Down syndrome mouse models EGCG development Dyrk1a
2015/5/22
Down syndrome (DS) is the result of trisomy of human chromosome 21 (Hsa 21) and occurs in approximately 1/700 live births. Mouse models of DS have been crucial in understanding the gene-phenotype rela...
Rescuing a broken heart: A tale of two Models of Neural Crest deficiency and its impact on In Utero Heart function and Embryonic Survival via the Beta-Adrenergic pathway
pax3 beta-adrenergic embryonic cardiac function
2015/5/21
Congenital heart defects occur in approximately one percent of births every year, which makes it the most frequently occurring congenital defect in patients. The aim of this project was to use two mut...