搜索结果: 1-9 共查到“NEP”相关记录9条 . 查询时间(0.125 秒)
人参皂苷Rb1对NEP基因启动子活性的影响
人参皂苷Rb1 神经内肽酶 启动子
2013/11/11
构建NEP启动子缺失体-荧光素酶报告基因质粒,探查神经内肽酶(NEP)基因启动子中与人参皂苷Rb1影响NEP启动子活性有关的位点。方法 用NEP基因5′上游启动区2.4kb片段和荧光素酶报告基因载体pGL3-basic构建NEP启动子-荧光素酶报告基因质粒pGL3-nep2.4;用Erase-a-Base System对pGL3-nep2.4质粒2.4kb DNA插入片段5′端进行缺失,构建N...
探讨苦参碱对人肾母细胞瘤SK-NEP-1 细胞存活及凋亡的影响,及降低顺铂化疗耐药性的可能作用机制。方法 将SK-NEP-1 细胞分为对照组、5 μg/mL 顺铂组、苦参碱组(0.5、1.0 和1.5 mg/mL)、苦参碱(0.5、1.0 和1.5 mg/mL)联合5 μg/mL 顺铂组。应用MTT 比色法检测各组细胞存活率,流式细胞仪检测各组细胞凋亡率,RT-PCR 检测各组细胞的PDCD4 m...
苦参碱联合顺铂对人肾母细胞瘤SK-NEP-1细胞PDCD4表达的影响
苦参碱 顺铂 程序性细胞死亡4 儿童
2014/11/10
探讨苦参碱对人肾母细胞瘤SK-NEP-1 细胞存活及凋亡的影响,及降低顺铂化疗耐药性的可能作用机制。方法 将SK-NEP-1 细胞分为对照组、5 μg/mL 顺铂组、苦参碱组(0.5、1.0 和1.5 mg/mL)、苦参碱(0.5、1.0 和1.5 mg/mL)联合5 μg/mL 顺铂组。应用MTT 比色法检测各组细胞存活率,流式细胞仪检测各组细胞凋亡率,RT-PCR 检测各组细胞的PDCD4 m...
研究脑中性内肽酶(NEP)基因外源表达对神经毒性物质β-淀粉样肽(Aβ25-35)诱导损伤的SK-N-SH细胞凋亡的抑制作用。方法 用脂质体法将含NEP的腺病毒载体转染高代次293细胞,制备高滴度病毒载体,感染Aβ25-35处理的外源损伤的人神经母细胞瘤细胞(SK-N-SH细胞),采用MTT法检测细胞存活率,采用流式细胞术分析细胞凋亡状态和细胞内活性氧水平,采用RT-PCR和Western ...
Environmental dependence of 8um luminosity functions of galaxies at z~0.8: Comparison between RXJ1716.4+6708 and the AKARI NEP deep field
galaxies evolution galaxies:interactions galaxies:starburst galaxies:peculiar galaxies:formation
2010/3/8
We aim to reveal environmental dependence of infrared luminosity functions (IR LFs) of galaxies at z~0.8 using the AKARI satellite. We construct restframe 8um IR LFs in the cluster region RXJ1716.4+6...
Evolution of Infrared Luminosity functions of Galaxies in the AKARI NEP-Deep field: Revealing the cosmic star formation history hidden by dust
galaxies evolution galaxies interactions galaxies:starburst galaxies peculiar galaxies formation
2010/3/8
Dust-obscured star-formation becomes much more important with increasing intensity, and increasing redshift. We aim to reveal cosmic star-formation history obscured by dust using deep infrared observa...
Factors Influencing Nep and Trash Transfer from the Sliver to the Rotor Yarn
nep trash OE yarn cotton fibres sliver
2009/2/5
Färber proposed the coefficient j to describe the nep and trash number; these are transferred to the yarn and identified as neps by the Uster tester in the sliver which feeds the OE spinning fram...
摘要 Neprilysin( NEP)是M13锌金属蛋白酶家族的一种Ⅱ型整合细胞膜糖蛋白.自从1974年首次被定义以来,NEP作为一种神经肽的降解酶,已经被发现广泛地存在于中枢神经系统以及外周各种组织中,并具有众多组织特异性功能.其中, NEP具有两大重要生理功能:一是NEP通过抑制细胞迁移增殖并诱导细胞程序性死亡具有抗肿瘤作用,这依赖它的酶学特性以及与涉及细胞信号转导通路的关键分子直接的蛋白-蛋...
Lenin and the currency competition Reflections on the NEP experience (1922-1924)
currency competition institutional complementarity economic history of Russia
2014/6/25
Institutional competition stirs the interest of economists following a certain cyclical pattern. In this context, it is very interesting to look back at the experience of Lenin and the Bolsheviks of a...