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Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype
malnutrition metabolome metabolic phenotype metabolome metabonomics microbiome microbiota, protein deficiency undernutrition
2018/12/18
Background: Environmental enteropathy, which is linked to undernutrition and chronic infections, affects the physical and mental growth of children in developing areas worldwide. Key to understanding ...
Heat Shock Protein Augmentation of Angelica gigas Nakai Root Hot Water Extract on Adipogenic Differentiation in Murine 3T3-L1 Preadipocytes
Angelica gigas Nakai Heat Shock Heat Shock Protein 3T3-L1 Adipogenesis
2016/5/19
There is a high association of heat shock on the alteration of energy and lipid metabolism. The alterations associated with thermal stress are composed of gene expression changes and adaptation throug...
Xenotropic Murine Leukemia Virus-Related Virus and RNase L R462Q Variants in Iranian Patients With Sporadic Prostate Cancer
Xenotropic Murine Leukemia Virus-Related Virus Polymorphism RNase L Prostate Cancer
2015/12/29
Background: Although several studies have confirmed the association of xenotropic murine leukemia virus-related virus (XMRV) and prostate cancer, this association is still controversial, as most studi...
Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model
: PTEN Hamartoma Tumour syndrome Cowden syndrome
2015/12/21
PTEN Hamartoma Tumour Syndrome (PHTS) includes Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome (BRRS),
and other conditions resulting from germline mutation of the PTEN tumour suppressor gene...
Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
arachidonic acid Calotropis gigantea ovalbumin
2015/7/21
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxyge...
Phospho-regulation and metastatic potential of Murine Double Minute 2
Metastasis Phosphorylation c-Src
2015/5/25
Murine double minute (Mdm2) is a highly modified and multi-faceted protein that is overexpressed in numerous human malignancies. It engages in many cellular activities and is essential for development...
Investigation of the action of phosphatase of regenerating liver on PTEN using murine models
Phosphatase of Regenerating Liver PTEN Mouse Models
2015/5/25
The addition and removal of phosphate groups is a key regulatory mechanism for many cellular processes. The balance between phosphorylation and dephosphorylation is delicate and must be maintained in ...
MicroRNAs are small RNA molecules that regulate expression of genes involved in development, cell differentiation, proliferation and death. It has been estimated that in eukaryotes, approximately 0.5 ...
Effects of Bai zhu san (Atractylodis macrocephalae) decoction on cellular immunity and Th1/Th2 cytokine ratio in a Mifepristone-induced murine abortion model
Bai zhu san mifepristone cytokine anti-abortive CD4+, CD8+T cells
2015/4/17
Chinese herbal medicine has been used as an anti-abortive treatment in farm animals for thousands of years. To investigate the anti-abortive functions and mechanisms of Bai zhu san (BZS) on mifepristo...
TLR agonists activate HPV11 E7-pulsed DCs to promote a specific T cell response in a murine model
HPV – human papillomavirus TLR – toll-like receptor DC – dendritic cell
2015/4/15
Some TLR agonists may up-regulate the activation of dendritic cells caused by viral antigenic peptides and antigen-specific cytotoxic T lymphocytes, which are crucial in HPV vaccine development. We in...
Susceptibility of selected murine and microtine species to infection by a wild strain of Francisella tularensis subsp. holoarctica
tularaemia survival time minimum infectious dose
2015/4/2
The purpose of this study was to compare susceptibility of BALB/c mice, common voles (Microtus arvalis) and yellow-necked mice (Apodemus flavicollis) to infection by a virulent Francisella tularensis ...
Multi-scale analysis of morphology, mechanics, and composition of collagen in murine osteogenesis imperfecta
Atomic force microscopy Raman spectroscopy Reference point indentation MicroCT crystallinity modulus
2015/1/12
Osteogenesis imperfecta is a rare congenital disease commonly characterized by brittle bones caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the...
The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma
Rhodiola crenulata highly metastatic murine mammary carcinoma
2014/12/12
The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma.
Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo: Role of the C-terminal polybasic domain
Rac GTPase NADPH oxidase
2014/12/12
The Rho family GTPase Rac acts as a molecular switch for signal transduction to regulate various cellular functions. Mice deficient in the hematopoietic-specific Rac2 isoform exhibit agonist-specific ...
The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties
Murine Retinoblastoma Cel mmunohistochemical Features
2014/11/25
HumanretinoblastomaarisesfromanundefineddevelopingretinalcellafterinactivationofRB1.ThisisemulatedinamurineretinoblastomamodelbyinactivationofpRBbyretinal-specificexpressionofsimianvirus40largeT-antig...