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生物谷MUCOSAL IMMUNOL：PRKAR2A缺失可通过增加IFN刺激的基因表达和调节肠道微生物群来保护小鼠免受实验性结肠炎的侵害（图）
PRKAR2A缺失；增加IFN刺激；肠道微生物群
2022/1/27
炎症性肠病(IBD)是一组慢性、复发性胃肠道炎症性疾病，主要包括克罗恩病和溃疡性结肠炎(UC)，尽管已证明遗传易感性、上皮屏障缺陷、免疫反应失调和肠道菌群失调等诸多因素参与了IBD的发生，但其发病机制仍未完全阐明。
Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis
inflammatory bowel disease mucosal inflammation tight junction ulcerative colitis vitamin D
2018/12/3
Background: Vitamin D exerts anti-inflammatory actions both in vitro and in murine models of colitis. In previous studies, we demonstrated that vitamin D protects against the development of colitis by...
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice
Herbal Extract Intestinal Barrier Inflammation Epidermal Growth Factor Pro-inflammatory Cytokines Metabolism
2016/5/20
To investigate the role of polysaccharide from Acanthopanax senticosus (ASPS) in preventing lipopolysaccharide (LPS)-induced intestinal injury, 18 mice (at 5 wk of age) were assigned to three groups w...
Effects of dietary conjugated linoleic acid on the duodenal mucosal immunity response and redox status of broiler chicks infected with Eimeria aceruvlina
CLA intestinal mucosal immunity oxidative stress broiler chick coccidiosis
2016/5/11
The present experiment investigated the effects of conjugated linoleic acid (CLA) on the growth performance, oocyst shedding, duodenal mucosal immune response, and redox status of broiler chicks infec...
Repair of cleft palate in a calf using polypropylene mesh and palatal mucosal flap: a case report
cleft palate surgical treatment calf
2015/4/7
The soft palate plays a critical role in the oral and pharyngeal phases of swallowing. Congenitally cleft soft palates (palatoschisis) in calves are rare and pose a serious challenge for surgical corr...
Effect of introducing the mucosal atomization device for fentanyl use in out-of-hospital pediatric trauma patients
device Emergency Medical Services fentanyl intranasal pain assessment pediatric trauma
2014/11/28
Background: Pain associated with pediatric trauma is often under-assessed and undertreated in the out-of-hospital setting. Administering an opioid such as fentanyl via the intranasal route is a safe a...
Background: Nowadays the importance of oral health to life quality is not obvious to anyone in our world. Oral lesions can interfere with daily social activities in involved patients through impacts o...
Long term outcomes comparing between endscopic mucosal resection and traditional gastrectomy for treatment of early gastric cancer
early gastric cancer endoscopic mucosal resection traditional gastrectomy histology
2009/7/15
Aims The purpose of this study was to confirm whether the endoscopical mucosal resection for early gastric replace to the traditional gastrectomy on the view point of long term patients' outcomes.
Me...
Endoscopic Mucosal Resection (EMR) for Colorectal Lesions and Lesion-lifted Condition as an Indicator of the Tumor Invasion
endoscopic mucosal resection (EMR) lesion-lifted condition colorectal neoplasm non-lifting sign pit pattern
2009/7/15
Utility and safety of EMR for colorectal lesions and lesion-lifted condition as an indicator of the tumor invasion were investigated. We investigated 672 cases and 708 lesions treated between 1993 and...
Primary mucosal desmoplastic melanoma of the gingiva
Desmoplastic melanoma oral mucosa p53 FasL caspase-3
2009/7/6
Desmoplastic melanoma (DM) is a very rare variant of malignant melanoma. Mucosal involvement in DM is exceedingly rare and the differential diagnosis is problematic for surgical pathologists. To the b...
The Effects of Vitamin E on Gastric Ulcers and Gastric Mucosal Barrier in Stress Induced Rats
Vitamin E Stress Gastric mucosal barrier
2009/7/6
Effects of vitamin E on gastric ulcers gastric mucosal barrier were in-vestigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stres...
The Protective Effect of Vitamins E and C on The Gastric Mucosal Barrier in Rats Irradiated With X-Rays
X-rays Gastric mucosal barrier Vitamin E Vitamin C
2009/7/1
The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into fo...
The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion
Ischemia and reperfusion stomach mucosal barrier allopurinol
2009/6/30
The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investiga...
The Frequency of Helicobacter pylori in Various Gastric Mucosal Appearances
Helicobacter pylori endoscopic appearance
2009/6/24
Our purpose was to investigate whether Helicobacter pylori (Hp) has a specific mucosal appearance. Eighty-eight (female / male: 53/35) patients included in the study underwent endoscopy to determine t...
Differential afferent sensitivity to mucosal lipopolysaccharide from Salmonella typhimurium and Escherichia coli in the rat jejunum
5-HT afferent nerve enteritis hypersensitivity mesenteric
2014/5/16
Postinfectious irritable bowel syndrome may develop subsequent to acute bacterial enteritis. We therefore hypothesized that intestinal afferents may develop hypersensitivity upon exposure to luminal l...