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浙江大学基础医学院张进课题组发表iPSC来源的CAR-Macrophage(CAR-iMac)可用于新型免疫细胞治疗（图）
浙江大学基础医学院 张进课题组 iPSC来源 CAR-Macrophage(CAR-iMac) 新型免疫细胞治疗
2020/11/20
2020年11月11日，浙江大学基础医学院干细胞与再生医学中心/浙江省良渚实验室的张进团队与浙江大学药学院翁勤洁团队以及浙江大学附属第一医院黄河团队联合在Journal of Hematology & Oncology(IF: 11.059) 杂志上发表标题为Pluripotent Stem Cell-derived CAR-Macrophage Cells with Antigen-depend...
An IL-4-dependent macrophage-iNKT cell circuit resolves sterile inflammation and is defective in mice with chronic granulomatous disease
macrophage-iNKT cel chronic granulomatous disease
2015/5/21
The immune system initiates tissue repair following injury. In response to sterile tissue injury, neutrophils infiltrate the tissue to remove tissue debris and subsequently undergo apoptosis. Proper c...
Polyamines and Alveolar Macrophage Apoptosis during Pneumocystis Pneumonia
Polyamines Alveolar Macrophage Apoptosis Pneumocystis Pneumonia
2015/1/28
Pneumocystis pneumonia (PCP) is the leading opportunistic disease in immunocompromised individuals, particularly in AIDS patients. The alveolar macrophage (AM) is the major type of cell responsible fo...
Polyamines and Alveolar Macrophage Apoptosis during Pneumocystis Pneumonia
Polyamines Alveolar Macrophage Apoptosis Pneumocystis Pneumonia
2015/1/19
Pneumocystis pneumonia (PCP) is the leading opportunistic disease in immunocompromised individuals, particularly in AIDS patients. The alveolar macrophage (AM) is the major type of cell responsible fo...
Modulation of Macrophage Responses to Borrelia Burgdorferi in Acute Murine Lyme Carditis
Macrophage Responses Borrelia Burgdorferi Acute Murine Lyme Carditis
2014/10/23
The Lyme disease spirochete Borrelia burgdorferi is the only known human pathogen that directly activates invariant natural killer T (iNKT) cells. The number and activation kinetics of iNKT cells vary...
Polymorphism, Expression of Natural Resistance-associated Macrophage Protein 1 Encoding Gene (NRAMP1) and Its Association with Immune Traits in Pigs
Natural Resistance-associated Macrophage Protein 1 (NRAMP1) Polymorphism Expression Association
2016/5/17
Natural resistance-associated macrophage protein 1 encoding gene (NRAMP1) plays an important role in immune response against intracellular pathogens. To evaluate the effects of NRAMP1 gene on immune c...
Macrophage phenotypes correspond with remodeling outcomes of various acellular dermal matrices
Acellular Dermal Matrix Derma Matrix AlloDerm Integra Derm Acell
2013/1/31
Macrophages have recently been characterized as having an M1 or M2 phenotype based on receptor expression, mechanism of activation and function. The effects of macrophage phenotype upon tissue remodel...
The adherence and functional properties of mice peritoneal macrophage phagocytic system with Phorbol Myristate Acetate stimulation and Nitroblue Tetrazolium reduction assay
Peritoneal Macrophages PMA stimulation NBT reduction assay
2009/12/29
Introduction: PMA is known to induce the differentiation of monocytes to macrophages. This agent also increases the killing effect of the monocytes/macrophages through oxidative burst and can be used ...
The adherence and functional properties of mice peritoneal macrophage phagocytic system with Phorbol Myristate Acetate stimulation and Nitroblue Tetrazolium reduction assay
Peritoneal Macrophages PMA stimulation NBT reduction assay
2009/12/29
Introduction: PMA is known to induce the differentiation of monocytes to macrophages. This agent also increases the killing effect of the monocytes/macrophages through oxidative burst and can be used ...
The Effect Of 8 Day Storage At 4˚C On Total Nucleated Cell Count,Cell Viability, And Granulocyte-Macrophage Colony Forming Unit Of Mobilized Peripheral Blood
peripheral blood progenitor cell refrigeration GM-CFU
2009/12/24
Background: Hematopoietic stem cell (HSC) transplantation has brought the possibility of the use of high dose chemotherapy in the treatment of malignant hematopoietic diseases. Short-term HSC preserva...
Accumulation of Element Ti in Macrophage-like RAW264 Cells Cultured in Medium with 1 ppm Ti and Effects on Cell Viability, SOD Production and TNF-α Secretion
Macrophage Titanium Phagocytosis
2009/9/15
The adverse effect of Ti on body-defense macrophage is not well understood. The aims of this study were twofold: (1) to examine the intracellular accumulation of Ti element; and (2) to measure the cel...
Pulmonary alveolar macrophage response to hyperbaric carbon monoxide exposure
carbon monoxide pulmonary CO animal guinea pig HBO
2009/7/17
The sublethal effects of carbon monoxide (CO) in hyperbaric environments have not been adequately characterized. A physiologically sensitive indicator of sublethal effects of a contaminant is the pulm...
Water-soluble Component in Dried Chrysanthemum Flower Stimulates Tumor Necrosis Factor-α Production by Mouse Macrophage-like Cell Line RAW264.7
chrysanthemum flowe TNF-α macrophage
2009/5/31
To clarify immunoregulatory activity of “Shiranui Himekiku” (Chrysanthemum indicam×Erigeron annus), we examined the effect on tumor necrosis factor α (TNF-α) production by mouse macrophage-like cell l...
Radical Scavenging Activity and Inhibition of Macrophage NO Production by Fukinolic Acid, a Main Phenolic Constituent in Japanese Butterbur（Petasites japonicus）
fukinolic acid scavenging activity ESR
2009/5/20
Four phenolic compounds were isolated from Japanese butterbur (Petasites japonicus) by preparative RP-HPLC technique, and were identified as chlorogenic acid (CGA), fukinolic acid (FA), 3,5-dicaffeoyl...
Dibutyltin（DBT）Dichloride Inhibits Cytokine Productions in Murine Macrophage Cell Line, J774.1.
dibutyltin macrophages tumor necrosis factor α interleukin-1β real time PCR ELISA
2009/3/23
The immune system is a target of dibutyltin (DBT) intoxication. We evaluated the effects of DBT dichloride in macrophages using the murine macrophage cell line, J774.1. Cultured J774.1 cells were expo...