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The DNA minor groove continues to be an important biological target in the development of anticancer, antiviral, and antimicrobial compounds. Among agents that target the minor groove, studies of well...
Metallopeptides of the general form M(II)∙Gly1-Gly2-His induce DNA strand scission via minor groove interactions. This peptide system can serve as a nucleic acid-targeted cleavage agent – either...
During 2004–2007 the efficacy of benzimidazole type drugs was studied on 14 sheep farms in the Czech Republic. The study was based on the evaluation of faecal egg count reduction test (FECRT), egg hat...
Moxidectin administered in January or February at a single dose was tested for efficacy in horses on two farms for 12 and 11 months, respectively. Horses were infected with cyathostomes naturally in t...
A simple and efficient method has been developed for the synthesis of some novel Schiff bases via the reaction of aromatic aldehydes with 2-aminobenzimidazole by using catalytic amount of M(NO3)2.xH2O...
New thermally stable photochromic fulgimides and benzimidazole[1,2-a]pyrrolidin-2-one derivatives of furylfulgide and thienylfulgide were prepared and their photochromic properties were investigated. ...
The aim of this study was to investigate the toxic effects of the human immunodeficiency virus-reverse transcriptase (HIV-RT) inhibitor 2-phenoxymethyl-5-chlorobenzimidazole on rat liver at the light ...
Carbendazim (methyl 2-benzimidazole carbamate; MBC) has been reported to disrupt the microtubules of Sertoli cells in the rat, suggesting that the cells exposed to carbendazim would fail to maintain...
The effects of carbendazim (methyl 2-benzimidazole carbamate) on the testis, efferent ductules, and sperm were determined in the adult rat after a single oral dose. Two experimental trials were perf...
Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity...
The study was conducted on 162 adult male Haemonchus contortus of sheep collected from Avikanagar, Jaipur and Bikaner regions to diagnose the benzimidazole (BZ) resistance in H. contortus. The BZ resi...
The title compound, C16H12N2S2, crystallizes in the monoclinic space group P21/n with Z = 4, a = 8.950 (5) Å, b = 9.141 (5) Å, c = 17.429 (5) Å and b = 93.638 (5)°. The benzimidazole...
Five Pt(II) complexes with the ligands 2-ethyl-/ or-benzyl-/ or-phenoxymethyl- and 1-methyl-2-hydroxymethyl- and 1-methyl-2-phenyl- benzimidazoles were synthesized and characterized by elemental analy...
Proton conducting properties of benzimidazole (BnIm) doped poly(vinylphosphonic acid) (PVPA) were studied. The doping ratio, x, which is the number of moles of BnIm per mole of polymer repeat unit, va...
The computational study of chromatographic separations has become increasingly important in recent years. It supplies useful information about the mechanism of chromatographic separations and the desi...

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