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Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019
coronavirus disease-19 (COVID-19) RNAemia IL-6 critically ill patients cytokine storm
2020/6/12
Although the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in respiratory specimens has been widely used to diagnose coronavirus disease 2019 (COVID-19), it is u...
Concentrations of serum amyloid A, haptoglobin,tumour necrosis factor and interleukin-1 and -6 in Anatolian buffaloes naturally infected with dermatophytosis
dermatophytosis anatolian buffaloes serum amyloid A haptoglobin cytokines
2016/3/24
Dermatophytosis is most frequently found in ruminants, in which non-pruritic periocular lesions are most typical, though generalised skin disease may develop. Accordingly, the infection causes major e...
Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
Role of the Dorsomedial Hypothalamus in Responses Evoked from the Preoptic Area and by Systemic Administration of Interleukin-1β
dorsomedial hypothalamus preoptic area hypothalamus paraventricular nucleus Fos body temperature heart rate ACTH
2015/5/21
Recent studies in anesthetized rats suggest that autonomic effects relating to thermoregulation that are evoked from the preoptic area (POA) may be mediated through activation of neurons in the dorsom...
A Common Variation in the Promoter Region of Interleukin-6 Gene Shows Association with Exercise Performance
Maximal oxygen uptake IL-6 polymorphism
2015/4/22
Skeletal muscle-derived interleukin-6 (IL-6) is a pleiotropic cytokine which regulates body metabolism during strenuous physical exercise. OBJECTIVE: The effect of a potentially functional single nucl...
Aerobic Training Activates Interleukin 10 for Colon Anticarcinogenic Effects
COLON CANCER PRENEOPLASTIC LESIONS INFLAMMATION PHYSICAL TRAINING
2017/4/20
Purpose: Physical exercise has been shown to be protective against colon carcinogenesis. Physical exercise, however, covers a wide range of modalities, from which different effects on the human body h...
Co-expression of IBV structural proteins and chicken interleukin-2 for DNA immunization
IBV S1 gene IL2 expression
2015/4/2
The S1 gene of IBV and the chicken IL-2 gene were ligated together into a eukaryotic expression vector pCI-neo for co-expression evaluation in vitro. The recombinant plasmids were transfected into Ver...
Interleukin-2 Expression in Lupoid and Usual Types of Old World Cutaneous Leishmaniasis
Leishmaniasis Interleukin-2 Granulomatous
2015/10/15
Background: Interleukin (IL)-2 plays a central role in T cell-dependent immune responses.
上海交通大学基础医学院王宏林课题组发现Interleukin-6通过作用于电压门控钙离子通道来调节间充质干细胞迁移的新机制
王宏林课题组 Interleukin-6 电压门控钙离子通道 间充质干细胞 迁移机制
2014/7/16
近日，国际学术期刊《Stem Cells》在线发表了上海交通大学基础医学院/上海市免疫学研究所王宏林课题组题为“Autocrine Interleukin-6 Drives Skin-Derived Mesenchymal Stem Cell Trafficking via Regulating Voltage-Gated Ca2+ Channels”的研究论文，报道了自分泌的IL-6在MSCs（...
The Role of Interleukin-12 on Modulating Myeloid-Derived Suppressor Cells
Interleukin-12 Immune Suppression
2015/5/21
More than 200,000 American women are diagnosed with breast cancer each year.
Although therapies effective in treating metastatic breast cancer currently exist, each year approximately 40,000 women d...
Interleukin-12 and Tumor Necrosis Factor-Β Gene Polymorphisms as Genetic Susceptibility Factors for Brucellosis in Iranian Patients
Brucella Genetic polymorphisms Interleukin-12 Tumor necrosis factor-β Iran
2015/9/21
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Kaempferol,a Tea Flavonol,Effect on Interleukin-2 Signal Transduction of Human T Cell Leukemia
cytokine tea (Camellia sinensis L.) NFAT (nuclear factor expression ofactivated T cell)
2009/9/9
CCRF-CEM and Jurkat E6-1, human T cell leukemia, produced interleukin (IL)-2 stimulated with
phorbol myristate acetate (PMA) and pokeweed mitogen (PWM). IL-2 cytokine production and
mRNA expression ...
An increasing body of evidence implicates proinflammatory cytokines in psychiatric disorders, namely, in depression. Of notice, recent studies showed that anti-inflammatory cytokines, such as IL-10, a...
Tumor Necrosis Factor-a and Interleukin-6 in Peritoneal Adhesion Formation
Peritoneal adhesion Tumor necrosis factor-a Interleukin-6
2009/7/2
This study was carried out to assess the role of tumor necrosis factor (TNF-a) and interleukin-6 (IL-6 ) in plasma and peritoneal fluid in higher rates of adhesion formation following standard bowel i...
Production and Purification of Monoclonal Antibodies to Human Interleukin-2 and Their Use for Immunoaffinity Purification of Recombinant Human Interleukin-2
Monoclonal antibody human interleukin-2 immunoaffinity purification
2009/6/26
Monoclonal antibodies (mAbs) are a powerful immunochemical tool. Today, the availability of mAbs with desired specificity enables ligand separation based upon the immunoaffinity technique. By using th...