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High-level Expression and Purification of Active Human FGF-2 in Escherichia coli by Codon and Culture Condition Optimization
Fibroblast Growth Factor 2 Codon Protein E. coli
2016/1/26
Background: Basic fibroblast growth factor (bFGF) is a member of a highly conserved superfamily of proteins that are involved in cell proliferation, differentiation, and migration.
Objectives: The ob...
Analysis of K-Ras Oncogene Codon 12 Mutations in a Series of Human Lung Cancers
K-ras codon 12 mutations on small cell lung cancers
2009/6/30
Lung cancer is the major cancer in Turkey; 45% of the deaths due to cancer in Turkish males are from lung cancer. There are 8 histopathological types of lung cancer, and most types have several genomi...
Identification of a Novel Frameshift Mutation [Codon 3 (+T)] in a Turkish Patient with b-Thalassemia Intermedia
b-thalassemia b-globin gene insertion frameshift mutation DNA sequencing
2009/6/22
b-Thalassemia, one of the most widespread genetic diseases in the world, is an autosomal recessive disease generally caused by point mutations in the b-globin gene that is located as a cluster on the ...
TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses
TP53 codon 72 apoptosis
2009/4/10
TP53 is the most common mutated gene in human cancers. Approximately half of all human malignancies exhibit TP53 mutations. The TP53 codon 72 polymorphism is a single-nucleotide polymorphism (SNP) in ...
Monitoring of the Sensitivity of Magnaporthe grisea to Metominostrobin 2001–2003: No Emergence of Resistant Strains and No Mutations at Codon 143 or 129 of the Cytochrome b Gene
metominostrobin cytochrome Magnaporthe grisea point mutation
2009/3/5
The sensitivity of Magnaporthe grisea to Metominostrobin (ORIBRIGHT®, a QoI fungicide) was examined. Six isolates collected in 1999, prior to the introduction of metominostrobin, were tested by ...
陕西汉族人p53 codon 72基因多态性与子宫颈鳞癌易患性的关系：病例对照研究。
马铃薯密码子用法分析及其在t-PA基因密码子改造上的应用Analysis of Codon Usage in Potato and Its Application in the Modification of t-PA Gene
马铃薯 t-PA 密码子用法 优越密码子 密码子改造
2008/1/10
摘要 采用bioperl-1.0 工具在红旗LINUX系统下自编了密码子分析软件；通过对马铃薯98个蛋白质编码基因序列（codon DNA sequence）的分析，计算出了马铃薯的密码子用法，并确定出了马铃薯的4个高表达优越密码子；依据马铃薯密码子用法和高表达优越密码子分析结果，对t-PA基因序列进行了密码子的改造，得到了具有马铃薯密码子使用特点的t-PA基因序列，从而为以马铃薯为生物反应器高效...
Association of a Single Codon Deletion in Bone Morphogenetic Protein 15 Gene with Prolificacy in Small Tail Han Sheep
Sheep Prolificacy Bone Morphogenetic Protein 15 Gene PCR-SSCP
2016/4/18
Small Tail Han Sheep has significant characteristics of high prolificacy and non-seasonal ovulatory activity and is an excellent local sheep breed in P. R. China. Recently a novel member of the transf...