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Adipose stromal cells enhance keratinocyte survival and migration in vitro, and graft revascularization in mouse wound healing model
ASC adipose stromal cell wound healing Integra burn adipose stem cell keratinocyte endothelial cell
2015/1/12
In the US, more than 1 million burn injuries are reported annually. About 45,000 injuries due to fires and burns result in hospitalization and ten percent of these result in death every year. Advances...
Nanoscale Morphology of Type I Collagen is Altered in the Brtl Mouse Model of Osteogenesis Imperfecta
AFM nanoscale
2014/11/6
Bone has a complex hierarchical structure that has evolved to serve structural and metabolic roles in the body. Due to the complexity of bone structure and the number of diseases which affect the ultr...
Effects of tissue hydration on nanoscale structural morphology and mechanics of individual Type I collagen fibrils in the Brtl mouse model of Osteogenesis Imperfecta
AFM Ultrastructure Genotype/phenotype D-periodic spacing Modulus Energy
2014/11/6
Type I collagen is the most abundant protein in mammals, and is a vital part of the extracellular matrix for numerous tissues. Despite collagen’s importance, little is known about its nanoscale morpho...
Localization of the VP2 Protein of Canine Parvovirus Type 2 on the Baculovirus Envelop and Its Immunogenicity in a Mouse Model
Canine Parvovirus Type 2 VP2 Protein Baculovirus gp64 TM and CTD Subunit Vaccine
2013/2/19
In this study, the full-length VP2 gene of canine parvovirus type 2 (CPV-2) was cloned into the pBacSC vector which possesses baculovirus transmembrane domain (gp64 TM) gene, baculovirus cytoplasmic d...
Cytotoxicity of seven recent dentine bonding agents on mouse 3T3 fibroblast cells
Cytotoxicity Bonding Agents Mouse 3T3 Fibroblast
2013/2/19
Today it is generally accepted that most bonding agents are cytotoxic. In this study the relative cytotoxicity of seven recent dentine bonding agents on mouse 3T3 fibroblast cells were investigated. M...
Prenatal and Postnatal Exposures to 1-Methyl-4-phenyl-1,2,3,6-tetra Hydropyridine (MPTP) Impaired Mouse Midbrain Dopamine System and May Produce a Predisposing and Inducing Model for Parkinson’s Disease
Parkinson’s Disease Midbrain -Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)
2013/1/29
Dopamine cell bodies in the substantia nigra of the midbrain and with their terminals projecting to the neostriatum form the nigrostriatum and these dopamine neurons degenerate in Parkinson’s disease ...
BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse
BRAK/CXCL14 oral carcinoma cells
2009/12/16
SCID mice are a model of human severe combined immunodeficiency disease and are deficient in B cell function in addition to T cell function. Tumors from other species are easily transplanted into SCID...
Effects of Japanese mistletoe lectin on cytokine gene expression in human colonic carcinoma cells and in the mouse intestine
mistletoe lectin cytokine gene expression
2009/12/16
Mistletoe lectins have various biological activities including anti-cancer and immunomodulatory effects. We previously isolated a lectin (ML-J) from Japanese mistletoe. In the present study, we examin...
The Effect of Bone Morphogenetic Protein 4 on the Differentiation of Mouse Embryonic Stem Cell to Erythroid Lineage in Serum Free and Serum Supplemented Media
embryonic stem cells bone morphogenetic protein-4 erythropoiesis serum free media
2009/10/26
This study was done to compare the effects of bone morphogenetic protein-4 (BMP-4) on mouse embryonic stem cells (ESC) differentiation to erythroid lineage in serum free and serum supplemented media. ...
Histochemical demonstration of monocarboxylate transporters in mouse brown adipose tissue
Histochemical demonstration monocarboxylate transporters
2009/12/16
Proton-coupled monocarboxylate transporters (MCTs) are essential for the transport of lactate, ketone bodies, and other monocarboxylates through the plasma membrane. The present immunohistochemical st...
Stem cell factor induces heterotopic accumulation of cells（heterotopia）in the mouse cerebral cortex
Stem cell factor heterotopic accumulation of cells (heterotopia) mouse cerebral cortex
2009/5/8
The stem cell factor (SCF)-c-kit signal transduction pathway plays an important role in the proliferation and migration of neural progenitor cells, but little is known about its function during the ...
Circadian expression of the Na+/H+ exchanger NHE3 in the mouse renal medulla
Circadian expression Na+/H+ exchanger NHE3 mouse renal medulla
2009/5/8
Renal tubular NHE3, the Na+/H+ exchanger, is a critical enzyme for electrolyte and acid-base homeostasis in the kidney. We previously demonstrated that the expression of this gene in the kidney foll...
Influence of muscle length on muscle atrophy in the mouse tibialis anterior and soleus muscles
muscle length muscle atrophy mouse tibialis anterior soleus muscles
2009/5/8
The tibialis anterior and soleus muscles were fixed at the stretched or shortened positions to examine the influence of muscle length on muscle atrophy. Mice were divided into control (C), hindlimb ...
Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells
Potential differentiation tumor bearing mouse CD11b+Gr-1+ immature myeloid cells suppressor macrophages immunostimulatory dendritic cells
2009/5/8
Evaluation of immunosuppressive tumor-escape mechanisms in tumor-bearing hosts is of great importance for the development of an efficient tumor immunotherapy. We document here the functional charact...
Different Effects of Regulatory Genes (tat, nef) of Human Immunodeficiency Virus Type 1 (HIV-1) on the Proliferation and Differentiation of Mouse Embryonic Stem Cells in vitro
embryonic stem cells regulatory genes of human immunodeficiency virus transfection embryoid bodies
2009/4/29
To examine the effects of the tat and nef regulatory genes of human immunodeficiency virus (HIV-1) on cell differentiation we used the mouse embryonic stem cells (ESC) as a model. Proliferation, embry...