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Health economics and health insurance aspects of Mendelian randomization
Health economics health insurance aspect Mendelian randomization
2018/12/19
We read with great interest the excellent paper of Haycock et al. (1) on the design, analysis, and interpretation of Mendelian randomization (MR) studies. We agree with the authors’ conclusions that t...
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
Mendelian randomization causality reverse causation confounding observational epidemiology evidence synthesis
2018/11/28
Mendelian randomization (MR) is an increasingly important tool for appraising causality in observational epidemiology. The technique exploits the principle that genotypes are not generally susceptible...
Is there a causal role for homocysteine concentration in blood pressure? A Mendelian randomization study
blood pressure cohort studies homocysteine Mendelian randomization molecular epidemiology
2018/11/23
Background: An understanding of whether homocysteine is a cause or a marker of increased blood pressure is relevant because blood homocysteine can be effectively lowered by safe and inexpensive interv...