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Morphologic changes induced by short-term ischemia in the rat testis are not affected by treatment with superoxide dismutase and catalase
short-term ischemia rat testis superoxide dismutase and catalase
2009/2/23
Short-term testicular ischemia was induced unilaterally by ligating the testicular artery for 60 or 100 minutes in adult rats. After 7 days, the rats were fixed by vascular perfusion. The effect of ...
Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity
Human spermatozoa liquid peroxidation superoxide production hydrogen peroxide production
2009/2/23
Spontaneous lipid peroxidation in washed human spermatozoa was induced by aerobic incubation at 32 C and measured by malonaldehyde production; loss of motility during the incubation was determined s...
Interaction between Ca2+, cyclic 3',5' adenosine monophosphate, the superoxide anion, and tyrosine phosphorylation pathways in the regulation of human sperm capacitation
Calmodulin phosphatase kinase
2009/2/17
In order to fertilize the egg, spermatozoa must go through the capacitation process where they experience Ca2+ uptake, increases in cyclic 3',5' adenosine monophosphate (cAMP) concentrations, supe...
Human sperm capacitation induced by biological fluids and progesterone, but not by NADH or NADPH, is associated with the production of superoxide anion
Spermatozoa MCLA reactive oxygen species sperm hyperactivation protein tyrosine
2009/2/17
Recent evidence indicated that human sperm capacitation is associated with an increased production of superoxide anion (O2.-). To further study the role and importance of O2.- in capacitation, we in...
Developmental expression of glutathione peroxidase, catalase, and manganese superoxide dismutase mRNAs during spermatogenesis in the mouse
Antioxidant enzymes gene expression testis translational regulation
2009/2/16
We have examined in mouse testis the steady-state levels of mRNAs encoding glutathione peroxidase (GSHPx), catalase (CAT), and superoxide dismutase 2 (SOD-2), three enzymes essential for the antio...
Mechanism of superoxide dismutase loss from human sperm cells during cryopreservation
superoxide dismutase loss human sperm cells cryopreservation
2009/2/12
Earlier studies on human sperm cryodamage have shown that plasma membrane stress is the primary process and that phospholipid peroxidation in cryopreserved samples is not inhibited by addition of an...
Identification and localization of copper-zinc superoxide dismutase gene expression in rat testicular development
Identification localization copper-zinc superoxide dismutase gene rat testicular development
2009/2/12
Reactive oxygen species are highly toxic agents that appear to have an important role in male infertility. In order to understand the potential for the testis to be protected from reactive oxygen, t...
Evidence for increased lipid peroxidative damage and loss of superoxide dismutase activity as a mode of sublethal cryodamage to human sperm during cryopreservation
superoxide dismutase activity sublethal cryodamage human sperm cryopreservation
2009/2/10
Cryopreservation of human sperm, now generally required in donor insemination programs, adversely affects the sperm in terms of standard sperm evaluation parameters and fertilizing ability. The fr...
Semenogelin, the main protein of semen coagulum, inhibits human sperm capacitation by interfering with the superoxide anion generated during this process
Protein tyrosine phosphorylation prostate-specific antigen
2008/12/29
Semenogelin (Sg), the major protein of the human semen coagulum, is present at high concentrations in seminal vesicle secretions. It is degraded by the prostate-specific antigen (PSA) to generate pe...
Survival and In Vitro Fertility of Boar Spermatozoa Frozen in the Presence of Superoxide Dismutase and/or Catalase
Antioxidants cryopreservation sperm porcine
2008/12/22
In the present study the potential benefit of reactive oxygen species (ROS)-scavenging enzymes superoxide dismutase (SOD) and catalase (CAT) when cryopreserving boar spermatozoa was evaluated. Poole...