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Development of transmembrane signaling in the fetal rat Leydig cell
transmembrane signaling fetal rat Leydig cell
2009/2/23
Gonadotropin binding to the adult Leydig cell activates a GTP binding protein that interacts with adenylate cyclase to increase cAMP production within the cell. The increased production of cAMP stim...
Mechanism of LHRH-stimulated steroidogenesis in rat Leydig cells：lipoxygenase products of arachidonic acid may not be involved
LHRH-stimulated steroidogenesis rat Leydig cells lipoxygenase products arachidonic acid
2009/2/23
Luteinizing hormone releasing hormone agonist, [(imBzl)-DHis6,Pro9,NEt]-LHRH (LHRH-A), caused a two to threefold increase in in vitro testosterone (T) secretion by rat Leydig cells. This LHRH-A-indu...
Testicular dysfunction in the adjuvant-induced arthritic rat
Testicular dysfunction adjuvant-induced arthritic rat
2009/2/23
Adjuvant-induced arthritis, an autoimmune disease similar to rheumatoid arthritis, was used to investigate possible mechanisms of immune system modulation of the reproductive system. This laboratory...
The automated analysis of rat sperm motility following subchronic epichlorohydrin administration：methodologic and statistical considerations
rat sperm motility subchronic epichlorohydrin administration methodologic and statistical considerations
2009/2/23
The automated analysis of sperm motion endpoints is potentially useful in identifying male reproductive toxicants and ultimately in predicting fertility in humans. The present study was designed to ...
Luteinizing hormone secretion by male rat pituitary cells perifused in vitro：effect of experimental left varicocele and orchiectomy
Luteinizing hormone secretion male rat pituitary cells
2009/2/23
It has been shown previously that experimental left varicocele in the rat, results in a bilateral decrease in intratesticular testosterone. In the present work, pituitary responsiveness to GnRH as a...
Mast cells in the testis, epididymis and accessory glands of the rat：effects of neonatal steroid treatment
Mast cells rat neonatal steroid treatment
2009/2/23
Mast cells in the testis of control adult rats were found almost exclusively around subcapsular blood vessels. Discrete mast cells were distributed throughout the stroma of the epididymis and sex ...
Transplantation of newborn rat testis under the kidney capsule of adult host as a model to study the structure and function of Leydig cells
newborn rat testis kidney capsule adult host Leydig cells
2009/2/23
Newborn rat testis was transplanted under the kidney capsule of adult castrated and uncastrated male rats to develop and characterize a model system for studies on Leydig cell development. Two weeks...
The action of calcitonin on the TM4 Sertoli cell line and on rat Sertoli cell-enriched cultures
TM4 Sertoli cell line rat Sertoli cell-enriched cultures
2009/2/23
The effects of synthetic salmon calcitonin on primary Sertoli cell-enriched cultures and on an established cell line (TM4 cells, derived from immature mouse Sertoli cells) were studied. Synthetic ...
The actions of calcitonin on the TM3 Leydig cell line and on rat Leydig cell-enriched cultures
calcitonin TM3 Leydig cell line rat Leydig cell-enriched cultures
2009/2/23
Studies demonstrating calcitonin receptors on Leydig cells have suggested that these cells may be one of the many sites affected by this peptide. To investigate this possibility, the effect of syn...
Possible role of elongated spermatids in control of stage-dependent changes in the diameter of the lumen of the rat seminiferous tubule
elongated spermatids stage-dependent changes rat seminiferous tubule
2009/2/23
Adult male rats were treated with a single dose of 650 mg/kg methoxy acetic acid to deplete the seminiferous tubules specifically of pachytene and later spermatocytes. The effect of this treatment a...
Cyclophosphamide in the male rat：new pattern of anomalies in the third generation
Cyclophosphamide male rat anomalies third generation
2009/2/23
Several abnormalities, such as postnatal deaths and behavioral impairments, have been previously reported in the progeny of male rats exposed to the cytostatic drug cyclophosphamide 60 days prior to...
Estradiol and plasminogen activator secretion by cultured rat Sertoli cells in response to melanocyte-stimulating hormones
Estradiol and plasminogen activator secretion cultured rat Sertoli cells melanocyte-stimulating hormones
2009/2/23
Pro-opiomelanocortin-derived peptides, alpha-MSH and beta-endorphin, are synthesized and secreted by Leydig cells, and are believed to have paracrine effects on Sertoli cells in the testis. Peptid...
Pituitary response to LHRH during chronic renal insufficiency in the male rat
Pituitary LHRH chronic renal insufficiency male rat
2009/2/23
Chronic renal insufficiency was induced in young adult male rats by a 2-step 5/6 nephrectomy. Four weeks after surgery the rats were anesthetized with ketamine and injected with saline or 1, 5, 10...
Testosterone dose-dependency of sexual and nonsexual behaviors in the gonadotropin-releasing hormone antagonist-treated male rat
Testosterone dose-dependency sexual nonsexual behaviors gonadotropin-releasing hormone male rat
2009/2/23
The testosterone dose-dependency of several mating and nonmating behaviors was examined in the male rat, chemically castrated with a GnRH antagonist analog. Graded doses of testosterone enanthate ...
Polyamine profiles in rat testis, germ cells and Sertoli cells during testicular maturation
Polyamine profiles rat testis germ cells Sertoli cells
2009/2/23
Polyamine cellular concentrations (putrescine, spermidine and spermine) in the rat testis and testicular cell types were determined by fluorescence spectroscopy of their dansyl derivatives. A met...