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Cytochalasin D inhibits penetration of hamster eggs by guinea pig and human spermatozoa
Cytochalasin D inhibits penetration hamster eggs guinea pig human spermatozoa
2009/2/23
Fertilization experiments using zona-free hamster eggs and spermatozoa from both guinea pig and human were conducted in the presence of cytochalasin D to evaluate the possible role of actin filame...
Partial sympathetic denervation of the rat epididymis permits fertilization but inhibits embryo development
Inferior mesenteric ganglion fertility spinal cord injury innervation spermatozoa intrauterine insemination
2009/2/17
The rat cauda epididymidis receives sympathetic innervation from the inferior mesenteric ganglion (IMG). We have previously demonstrated that surgical removal of the IMG and proximal hypogastric ner...
Sertoli cell secretion of a factor that inhibits the incorporation of 3H-thymidine into cells in vitro
Sertoli cell cell proliferation DNA synthesis
2009/2/12
Rat Sertoli cells secrete a low molecular weight factor in vitro that inhibits the incorporation of 3H-thymidine into cells. Although the addition of Sertoli cell-conditioned medium (rSCCM) result...
Atrial natriuretic factor inhibits the phosphorylation of protein kinase C in plasma membrane preparations of cultured Leydig tumor cells
Atrial natriuretic factor protein kinase C Leydig tumor cells cGMP plasma membranes
2009/2/12
The peptide hormone atrial natriuretic factor (ANF) exerts its effect in a receptor-mediated fashion and the membrane-bound form of guanylate cyclase represents a biologically active ANF receptor;...
Protein kinase C increases 11beta-hydroxysteroid dehydrogenase oxidation and inhibits reduction in rat Leydig cells
Calcium calmodulin glucocorticoid action oxidoreductases
2008/12/30
Glucocorticoid hormone controls Leydig cell steroidogenic function through a receptor-mediated mechanism. The enzyme 11beta-hydroxysteroid dehydrogenase (11betaHSD) plays an important role in Leydig...
Mullerian inhibiting substance inhibits testosterone synthesis in adult rats
Anti-Mu llerian hormone primary Leydig cells
2008/12/29
Mullerian inhibiting substance (MIS) is a gonadal hormone that causes regression of the Mullerian ducts during male sexual differentiation. Postnatally, MIS inhibits the proliferation and differen...
Semenogelin, the main protein of semen coagulum, inhibits human sperm capacitation by interfering with the superoxide anion generated during this process
Protein tyrosine phosphorylation prostate-specific antigen
2008/12/29
Semenogelin (Sg), the major protein of the human semen coagulum, is present at high concentrations in seminal vesicle secretions. It is degraded by the prostate-specific antigen (PSA) to generate pe...
Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells
Melatonin inhibits steroidogenic protein steroidogenesis MA-10 cells
2008/12/26
The effects of melatonin on steroidogenesis and steroidogenic acute regulatory (StAR) protein expression were investigated in MA-10 mouse Leydig tumor cells. MA-10 cells were treated with human chorio...
Protein kinase C increases 11beta-hydroxysteroid dehydrogenase oxidation and inhibits reduction in rat Leydig cells
Protein kinase C 11beta-hydroxysteroid dehydrogenase oxidation inhibits rat Leydig cells
2008/12/1
Glucocorticoid hormone controls Leydig cell steroidogenic function through a receptor-mediated mechanism. The enzyme 11beta-hydroxysteroid dehydrogenase (11betaHSD) plays an important role in Leyd...