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Identification of human glandular kallikrein hK2 from LNCaP cells
Prostate carcinoma rnonoclonal antibody seminal
2009/2/16
Based on studies indicating that human glandular kallikrein (hK2) mRNA is present in the prostate, we prepared a monoclonal antibody to a synthetic peptide corresponding to the 41-56 region of hK2 t...
Effects of triptorelin, a gonadotropin-releasing hormone agonist, on the human prostatic cell lines PC3 and LNCaP
triptorelin a gonadotropin-releasing hormone agonist human prostatic cell lines PC3 LNCaP
2008/12/25
Some analogues of gonadotropin-releasing hormone (GnRH) influence the in vitro proliferation of cultured human cells by complex interactions that are only partially understood. This study explored t...
Androgens Induce Increases in Intracellular Calcium Via a G Protein–Coupled Receptor in LNCaP Prostate Cancer Cells
5-Dihydrostestosterone Ca2+ GPCR
2008/12/24
The receptor mechanism of testosterone-induced nongenomic Ca2+ signaling in prostate cancer cells is poorly understood. In this study we investigated androgen-induced intracellular Ca2+ increa...
Zinc and Metallothionein Levels and Expression of Zinc Transporters in Androgen-Independent Subline of LNCaP Cells
Hormone-refractory metallothionein ZnT1 ZnT3
2008/12/22
Zinc levels in the prostate have been reported to be associated with the development and progression of malignant prostate cells. To investigate the reason why the zinc content decreases during th...
Androgen-Induced Prostate-Specific Antigen Gene Expression Is Mediated via Dihydrotestosterone in LNCaP Cells
5-Reductase isozymes testosterone prostatic tumor cells
2008/12/19
Prostate cancer is a leading cause of cancer death in American males. Androgens play an essential role in prostate development, growth and pathogenesis of benign prostate hyperplasia, and prostate c...