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IL-13/IL-13 Receptor Interaction, an Emerging Therapeutic Target in Allergic Disease
allergy antagonist asthma drug design interleukin-13 receptor
2010/11/19
Interleukin (IL)-13 is a Th-2 cytokine, known to be involved in allergic diseases. Although IL-13 and another Th-2 cytokine, IL-4, share receptors and signal pathways, having similar biological proper...
The High Affinity IgE Receptor (FcεRI) as a Target for Anti-allergic Agents
FcεRI gene expression humanized anti-FcεRI α chain antibody IgE soluble α
2010/11/19
Prevention of the effector cell activation via high affinity IgE receptor (FcεRI) is thought to be a straightforward strategy for suppressing the allergic reaction. Among the numerous methods to preve...