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Small-Molecule Hydrophobic Tagging Induced Degradation of HaloTag Fusion Proteins
Degradation of HaloTag Fusion Proteins Small-Molecule Hydrophobic Tagging
2014/11/25
The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic ...
Does Disc Space Height of Fused Segment Affect Adjacent Disc Degeneration in Anterior Lumbar Interbody Fusion? A Radiological Study
Adjacent segment degeneration Anterior lumbar interbody fusion
2015/9/25
Background: The restoration of disc space height (DSH) is essential in anterior lumbar interbody fusion (ALIF), while it is unclear whether the reduction of DSH may alter the mechanical status and adv...
中国医学科学院实验血液学国家重点实验室王建祥课题组在Leukemia期刊上发表"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene"
血液学 国家重点实验室 王建祥 课题组 Leukemia期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Treatment of Cervical Spondylosis by Anterior Subtotal Vertebrectomy and Iliac Bone Fusion
Cervical spondylosis myelopathy radiculopathy vertebrectomy
2009/7/1
There is no ideal surgical technique for cervical spondylosis. The choice of surgical procedure remains controversial. A series of 25 patients who had undergone subtotal vertebrectomy and iliac bone f...
Three-level anterior cervical discectomy and fusion in elderly patients with wedge shaped tricortical autologous graft: A consecutive prospective series
Anterior discectomy elderly patients plating three-level cervical spine disease wedge-shaped autograft
2008/11/25
Background: Treatment of multilevel cervical spondylotic myelopathy/radiculopathy is a matter of debate, more so in elderly patients due to compromised physiology. We evaluated the clinical and radiol...