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Reactive Oxygen Species, Mitochondria, and Endothelial Cell Death during In Vitro Simulated Dives
SCUBA DIVING OXIDATIVE STRESS REACTIVE OXYGEN SPECIES MITOCHONDRIAL MEMBRANE POTENTIAL CELL DEATH ENDOTHELIAL DYSFUNCTION
2017/4/19
Purpose: Excessive reactive oxygen species (ROS) is considered a consequence of hyperoxia and a major contributor to diving-derived vascular endothelial damage and decompression sickness. The aims of ...
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
APE/Ref-1 reactive oxygen species redox
2014/12/12
Reactive oxygen species (ROS) arise through normal cellular aerobic respiration, and, in combination with external sources such as ionizing radiation, cigarette tar and smoke, and particulate matter g...
Implications of Ape1 in reactive oxygen signaling response following cisplatin treatment of dorsal root ganglion neurons
ROS APE1 base excision repair neurotoxicity
2014/12/12
Peripheral neuropathy is one of the major side-effects of the anticancer drug, cisplatin. Although previous work suggests that this neuropathy correlates with formation of DNA adducts in sensory neuro...
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
APE1 Ref-1
2014/12/12
Apurinic apyrimidinic endonuclease redox effector factor-1 (APE1/Ref-1) is involved both in the base excision repair (BER) of DNA lesions and in the eukaryotic transcriptional regulation. APE1/Ref-1 i...
Reactive oxygen species induced oxidative stress, neuronal apoptosis and alternative death pathways
Apoptosis Caspases Cell Death Mitochondria PCBs Reactive Oxygen Species
2013/1/28
Reactive oxygen species (ROS) are produced as a byproduct of cellular metabolic pathways and function as a critical second messenger in a variety of intracellular signaling pathways. The excessive int...
The Role of Reactive Oxygen Species in Immunopathogenesis of Rheumatoid Arthritis
CIA Immunopathogenesis Rheumatoid arthritis ROS
2009/12/11
Rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. It is characterized by chronic...
The Role of Reactive Oxygen Species in Immunopathogenesis of Rheumatoid Arthritis
CIA Immunopathogenesis Rheumatoid arthritis ROS
2009/12/11
Rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. It is characterized by chronic...
In Situ Real-Time Chemiluminescence Imaging of Reactive Oxygen Species Formation from Cardiomyocytes
Chemiluminescence Cardiomyocytes
2009/9/4
We have applied the highly sensitive chemiluminescence (CL) imaging technique to investigate the in situ ROS formation in cultured monolayers of rat H9c2 cardiomyocytes. Photon emission was detected v...
Ischemia-Reperfusion Injury,Reactive Oxygen Metabolites,and the Surgeon
Ischemia-Reperfusion Injury Reactive Oxygen Metabolites
2009/7/3
Surgeons are confronted with ischemia-reperfusion (IR) injury more often than they anticipate. Hypoperfusion associated with hypotension and hypovolemia is probably the most common cause of non-occlus...
Reactive oxygen species and cell signaling with lung ischemia
Anoxia Animal mice mice knockout
2009/6/4
This presentation concerns reactive oxygen species (ROS) and cell signaling in lung ischemia and during reperfusion. A number of years ago, McCord, Granger and others described the now-classic paradig...
Does hydrostatic pressure have an effect on reactive oxygen species in the eel?
reactive oxygen species ROS metabolism hydrostatic pressure migration silvering process animal yellow eel hydroxyl radical superoxyde dismutase catalase malondialdehyde antioxidant enzyme
2009/6/2
Eels are submitted to hydrostatic pressure (HP) during their spawning migration (about 6000 Km). Before migration, they change from the yellow to the silver stage (silvering process). The effects of H...
Celecoxib Enhances the Chemotherapeutic Response of Cisplatin and TNF-α in SiHa Cells through Reactive Oxygen Species-Mediated Mitochondrial Pathway
cervical cancer apoptosis celecoxib cisplatin TNF-α mitochondria
2009/4/20
Recently, many studies have shown that celecoxib induces apoptosis in various cancer cells by different mechanisms depending on the cell type. This study examined the effect of the selective COX-2 inh...
Effects of reactive oxygen species on in vitro filtration of water and albumin across glomerular basement membrane
reactive oxygen species water and albumin across glomerular basement membrane
2009/4/20
Most of the interest in the glomerular basement membrane (GBM) stems from the observation that it undergoes morphological changes in renal disease. Studies on persistent proteinuria in experi...
Oxidative damage of prion protein induced by reactive oxygen species
Oxidative damage prion protein induced reactive oxygen species
2009/4/1
Prion protein (PrP) consists of an amino-terminal domain containing a series of octapeptide repeats with the consensus sequence PHGGGWGQ and a carboxyl-terminal domain composed of three α-helices and ...
Analysis of the relationship between defective sperm function and the generation of reactive oxygen species in cases of oligozoospermia
defective sperm function reactive oxygen species oligozoospermia
2009/2/23
The ability of human spermatozoa to exhibit sperm-oocyte fusion in response to the ionophore, A23187, was examined in relation to the capacity of these cells to generate reactive oxygen species. I...