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搜索结果: 1-12 共查到医学 methylenetetrahydrofolate reductase相关记录12条 . 查询时间(0.062 秒)
Down syndrome, or trisomy 21, is a complex genetic disease resulting from the presence of 3 copies of chromosome 21. The origin of the extra chromosome is maternal in 95% of cases and is due to the...
Woodside et al (1) recently published an interesting study of the effects of folic acid and vitamins B-6 and B-12 on total plasma homocysteine (tHcy) concentrations in 132 men stratified for the co...
Background: Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) i...
The TT genotype was associated with higher homocysteine and lower plasma folate than the CC and CT genotypes in both cases and controls and a nonsignificant increase in vascular disease risk (1.26; 95...
Background: The association of MTHFR and metabolic syndrome (MS) has been shown in special groups of diabetic and schizophrenic subjects, but no single study has investigated this relation in metaboli...
Background: Pseudoexfoliation (PEX) syndrome leads to elevated intraocular pressure and consequent glaucomatous damage of the optic nerve. This study was performed to investigate the frequency of MTHF...
Background: Several studies showed that elevated plasma homocysteine level is a risk factor for coronary artery disease (CAD). A common polymorphism C677T of methylenetetrahydrofolate reductase (MTHFR...
The objective of the study was to assess the effect of the polymorphism on the relations among folate intake, plasma folate concentration, and total plasma homocysteine (tHcy) concentration.
BackgroundMethylenetetrahydrofolate reductase (MTHFR; EC 1.7.99.5) supplies the folate needed for the metabolism of homocysteine. A reduction in MTHFR activity, as occurs in the homozygous...
BackgroundLow folate status and elevated plasma homocysteine are associated with increased risk of neural tube defects and cardiovascular disease. Homocysteine responses to folate may be influe...
BackgroundElevated plasma total homocysteine (tHcy) is a risk factor for vascular disease and neural tube defects. The polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase...
Background: Several studies have examined the association of the methylenetetrahydrofolate reductase (MTHFR) genotype with plasma homocysteine in adults, but few studies have been performed in chil...

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