搜索结果: 1-12 共查到“医学 methylenetetrahydrofolate reductase”相关记录12条 . 查询时间(0.062 秒)
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
folate homocysteine mutation
2016/6/1
Down syndrome, or trisomy 21, is a complex
genetic disease resulting from the presence of 3 copies of chromosome
21. The origin of the extra chromosome is maternal in
95% of cases and is due to the...
Effects of folic acid on homocysteine in persons classified by methylenetetrahydrofolate reductase genotype
folic acid vitamins B-6
2016/5/31
Woodside et al (1) recently published an interesting study of
the effects of folic acid and vitamins B-6 and B-12 on total plasma
homocysteine (tHcy) concentrations in 132 men stratified for
the co...
Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphism in Iranian Women With Idiopathic Recurrent Pregnancy Losses
Methylenetetrahydrofolate Reductase Thrombophilia Pregnancy
2015/10/13
Background: Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) i...
Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project
MTHFR ischemic heart disease vascular disease risk
2016/12/27
The TT genotype was associated with higher homocysteine and lower plasma folate than the CC and CT genotypes in both cases and controls and a nonsignificant increase in vascular disease risk (1.26; 95...
Association of Methylenetetrahydrofolate Reductase gene Polymorphism (C677T) with Metabolic Syndrome in an Iranian Population: Tehran Homocysteine Survey
MTHFR Metabolic syndrome Population
2009/11/26
Background: The association of MTHFR and metabolic syndrome (MS) has been shown in special groups of diabetic and schizophrenic subjects, but no single study has investigated this relation in metaboli...
Methylenetetrahydrofolate Reductase Gene Polymorphism and Homocysteine Level in Patients with Pseudoexfoliation and Pseudoexfoliation Glaucoma in Southern Iran
Pseudoexfoliation Pseudoexfoliation glaucoma Gene Polymorphism
2015/9/18
Background: Pseudoexfoliation (PEX) syndrome leads to elevated intraocular pressure and consequent glaucomatous damage of the optic nerve. This study was performed to investigate the frequency of MTHF...
Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T Polymorphism Is Associated with Coronary Atherosclerosis Disease in a Sample of Iranian Patients
MTHFR CAD Folate Folic acid Homocysteine
2010/4/6
Background: Several studies showed that elevated plasma homocysteine level is a risk factor for coronary artery disease (CAD). A common polymorphism C677T of methylenetetrahydrofolate reductase (MTHFR...
Effect of the methylenetetrahydrofolate reductase 677C→T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample
total homocysteine tHcy metabolism
2016/12/29
The objective of the study was to assess the effect of the polymorphism on the relations among folate intake, plasma folate concentration, and total plasma homocysteine (tHcy) concentration.
Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status:implications for riboflavin requirements
Homocysteine riboflavin methylenetetrahydrofolate reductase folate folic acid neural tube defects MTHFR genotype
2016/12/19
Background: Methylenetetrahydrofolate reductase (MTHFR; EC 1.7.99.5) supplies the folate needed for the metabolism of homocysteine. A reduction in MTHFR activity, as occurs in the homozygous...
Methylenetetrahydrofolate reductase 677C→T genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement:a randomized controlled trial
Folic acid folate homocysteine MTHFR genotype methylenetetrahydrofolate reductase fortification healthy population dietary intake neural tube defects
2016/12/19
Background: Low folate status and elevated plasma homocysteine are associated with increased risk of neural tube defects and cardiovascular disease. Homocysteine responses to folate may be influe...
5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women
MTHFR genotype homocysteine folic acid methyltetrahydrofolate methylenetetrahydrofolate reductase supplementation women
2016/12/17
Background: Elevated plasma total homocysteine (tHcy) is a risk factor for vascular disease and neural tube defects. The polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase...
Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children
methylenetetrahydrofolate reductase genotype age vitamin B-12
2016/6/8
Background: Several studies have examined the association of
the methylenetetrahydrofolate reductase (MTHFR) genotype
with plasma homocysteine in adults, but few studies have been
performed in chil...