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2019年11月13日，浙江大学医学院附属口腔医院王慧明教授团队在STEM CELLs（干细胞领域权威期刊之一）上在线发表题为“KLF2+ stemness maintains human mesenchymal stem cells in bone regeneration”的研究论文，首次提出采用KLF2作为人骨髓间充质干细胞(hMSCs)体外标志物，并研究KLF2+hMSCs在血管再生和骨组...
The sixth Gordon Conference on Stem Cells and Cancer will focus on how stem cell aging influences the initiation and progression of cancer. Aging leads to progressive impairments in stem cell function...
Researchers use stem cells to regenerate the external layer of a human heart
Researchers stem cells regenerate the external layer human heart
2017/2/16
A process using human stem cells can generate the cells that cover the external surface of a human heart — epicardium cells — according to a multidisciplinary team of researchers."In 2012, we discover...
Prenatal Maternal Physical Activity and Stem Cells in Umbilical Cord Blood
REAST STEM CELLS CARDIOVASCULAR FITNESS EARLY LIFE DETERMINANTS
2017/4/13
Purpose: Early life processes, through influence on fetal stem cells, affect postnatal and adult health outcomes. This study examines the effects of physical activity before and during pregnancy on st...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
Tsg-6 : an inducible mediator of paracrine anti-inflammatory and myeloprotective effects of adipose stem cells
Adipose stem cell inflammation TSG-6 hematopoiesis smoking
2015/5/22
Tumor necrosis factor-induced protein 6 (TSG-6) has been shown to mitigate inflammation. Its presence in the secretome of adipose stem / stromal cells (ASC) and its role in activities of ASC have been...
Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Molecular switch matures heart cells derived from stem cells（图）
Molecular switch matures heart cells derived stem cells
2015/5/25
A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered. The discovery should help scientist better unde...
Mesenchymal Stem Cells Augment the Adaptive Response to Eccentric Exercise
A7 INTEGRIN SATELLITE CELLS STEM CELL ANTIGEN-1 DOWNHILL RUNNING REPAIR GROWTH
2017/4/14
Purpose: The α7β1 integrin is a transmembrane protein expressed in the skeletal muscle that can link the actin cytoskeleton to the surrounding basal lamina. We have previously demonstrated that transg...
UCSF Team Finds Key to Making Neurons From Stem Cells（图）
UCSF Team Making Neurons Stem Cells
2015/3/25
A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.The research, led by neurosurgeon...
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
APE1 DNA repair hematopoiesis
2014/12/12
Ape1 is a molecule with dual functions in DNA repair and redox regulation of transcription factors. In Ape1-deficient mice, embryos do not survive beyond embryonic day 9, indicating that this molecule...
The University of Queensland researchers grow kidney from stem cells
kidney from stem cells renal disease
2014/7/9
University of Queensland researchers have made a major leap forward in treating renal disease, today announcing they have grown a kidney using stem cells.
Does DNA Methylation Plays a Critical Role in Osteoblastic Differentiation of Mesenchymal Stem Cells (MSCs)?
Mesenchymal Stromal Cells Cell Differentiation Osteoblastic
2015/10/8
Mesenchymal stem cells (MSCs) are characterized by ability to differentiate into several cell types and self-renewability. These stem cells have a limited capacity in cell lineage differentiation incl...
Tissue Engineering Using Human Mineralized Bone Xenograft and Bone Marrow Mesenchymal Stem Cells Allograft in Healing of Tibial Fracture of Experimental Rabbit Model
Bone Xenograft Allograft Mesenchymal stem cells Healing Rabbit
2015/9/25
Background: Bone healing and its reconstruction in fractures, especially in long bones are of particular importance in regenerative medicine. This study compares the bone healing rate after a human xe...
CD4+ T cell mediated tumor immunity following transplantation of TRP-1 TCR gene modified hematopoietic stem cells
Melanocyte Differentiation Antigen Lentiviral Vectors
2015/5/21
Immunotherapy for cancer has held much promise as a potent modality of cancer treatment. The ability to selectively destroy diseased cells and leave healthy cells unharmed has been the goal of cancer ...