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Background: Alterations in p53 and p27KIP1 have been documented as important events in the carcinogenesis of various cancers, but their prognostic role in oral squamous cell carcinoma (OSCC) remains c...
Estimation of serological and salivary biomarkers in patients with oral squamous cell carcinoma, premalignant lesions & conditions.
Background and Aim: A single nucleotide polymorphism at codon 72 of the p53 gene alters the p53 protein structure and affects its activity. This polymorphism depends on geographic regions and race. Al...
Introduction: Oral leukoplakia, submucous fibrosis (OSMF), oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC) are the commonly occurring oral diseases, with characteristic clinical and h...
Oral squamous cell carcinoma accounts for 90% to 95% of all oral malignancies. Though its diagnosis seldom presents difficulty, it is the cancer staging and histopathological grading that are importan...
Around the world, 200,000 people a year are affected by oral cancer, and the incidence of this disease is 10 times higher in India than Japan, mainly due to the custom of chewing tobacco. Loss of hete...
Around the world, 200,000 people a year are affected by oral cancer, and the incidence of this disease is 10 times higher in India than Japan, mainly due to the custom of chewing tobacco. Loss of hete...
Allelic imbalance or loss of heterozygosity (LOH) and microsatellite instability (MSI) have been used to identify regions on chromosomes that may contain putative tumor suppressor genes. To obtain a d...
Allelic imbalance or loss of heterozygosity (LOH) and microsatellite instability (MSI) have been used to identify regions on chromosomes that may contain putative tumor suppressor genes. To obtain a d...

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