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Objective: To evaluate the efficacy of imatinib in chronic myeloid leukemia patients with variant translocations. Methods: Forty eight chronic myeloid leukemia patients carrying variant translocations...
Myeloid-derived suppressor cells comprise a heterogeneous population of immature immune cells that expand during the course of cancer progression. These cells adopt an immunosuppressive phenotype that...
The present study is aimed to determine the role of calcium signaling evoked by the oxygen radical, hydrogen peroxide (H2O2) and the specific inhibitor of calcium reuptake thapsigargin on apoptosis in...
Cancer chemotherapy in chronic carriers of hepatitis B virus surface antigen (HBsAg) is known to promote viral replication,and when immunosuppressive treatment is stopped the return of immunocompetenc...
Aims: Drug resistance is a major obstacle for a successful cancer therapy. Cell adhesion mediated drug resistance (CAM-DR) is a novel type of drug resistance and generated via interaction of cancer ce...
Evaluation of immunosuppressive tumor-escape mechanisms in tumor-bearing hosts is of great importance for the development of an efficient tumor immunotherapy. We document here the functional charact...
专著信息 书名 Dendritic cells (DC) induced from acute myeloid leukemia (AML) cells with cytokine cocktails. 语种 英文 撰写或编译 作者 Yan KH,You SG,Bian SG,Ma GJ,Ge W,Ma S,Liu SH,Zhao RCH 第一作者单位 出版社 Zhonghua Xue Ye Xu...
Introduction: Reverse transcriptase-polymerase chain reaction (RT-PCR) assay is a useful tool for the detection of fusion transcript resulting from specific chromosomal translocation of the leukemia c...
Acute myeloid leukemia (AML) is a major indication for hematopoietic stem cell transplantation (HSCT). Here we describe more in general the present status and new directions in the therapy for AML.
Treatment of acute myeloid leukemia (AML): Recent results and new directions。

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