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K亚群禽白血病病毒5'LTR序列及启动活性分析
ALV-K 致病性 LTR 启动活性
2018/5/4
通过对ALV-K 5'LTR序列及其启动活性比较分析,以探究5'LTR对ALV-K体外复制能力的影响。选取广东某黄羽祖代种鸡场健康鸡群中分离到的ALV-K(GDFX0601)毒株作为研究对象,将其5'LTR核苷酸序列与国内外不同亚群ALV分离株比较分析,并将该ALV-K接种DF-1细胞,采用ELISA对细胞培养上清进行ALV p27抗原检测以分析其在DF-1细胞上的复制能力,还分别将ALV-K(G...
Investigation of Deletion Variation and Methylation Patterns in the 5' LTR of Porcine Endogenous Retroviruses
Pigs Long Terminal Repeat (LTR) Porcine Endogenous Retroviruses (PERVs) Xenotransplantation
2016/4/28
The xenotransplantation of pig organs and cells can be related with a risk of transmission of infectious diseases to human. Previous findings indicate that the regulatory region of PERV for retroviral...