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Effects of selenium on selenoprotein synthesis and antioxidant parameters of bovine mammary epithelial cells
trace element dairy cows glutathione peroxidase thioredoxin reductase antioxidant function
2018/11/23
This study aimed to investigate the effects of selenium (Se) on the selenoproteins synthesis and antioxidant parameters of bovine mammary epithelial cells (BMECs). The experiment was conducted as a si...
Protection of Bovine Mammary Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Cell Damage by Selenium
selenomethionine selenoprotein synthesis arachidonic acid metabolism mitogen-activated protein kinase
2018/3/5
The uncontrolled release of arachidonic acid (ARA) and its metabolism by lipoxygenase (LOX) pathway can induce
and aggravate cellular oxidative stress. Selenium (Se) is an integral part of some antio...
Identification and characterization of bovine mammary peptide transporters in response to tripeptide and lactogenic hormone treatment
bovine mammary gland PepT RT-PCR lactogen
2017/6/22
Oligopeptide transportation is mediated by the peptide transporter (PepT), which consists of two isoforms, PepT1 and PepT2. Because PepT play essential roles in amino acid metabolism and cell growth, ...
Innate defense capability of challenged primary bovine mammary epithelial cells after an induced negative energy balance in vivo
pbMEC mastitis energy deficit E. coli
2015/6/23
Negative energy balance (NEB), if followed by metabolic imbalance, is a common problem in
high-yielding dairy cows frequently associated with inflammation of the mammary gland. After entering the
...
Immunohistochemical localization of adhesion molecules (CD62 and CD18) in the mammary gland of dairy cows
cattle L-selectin β2-integrin mastitis
2015/6/4
Localization of the L-selectin (CD62L) and β2-integrin (CD18) bearing cells in different tissues of the bovine mammary gland was examined. Five dairy cows of Holstein-Friesian breed in the middle of t...
Molecular Cloning and Characterization of a New C-type Lysozyme Gene from Yak Mammary Tissue
Yak Mammary Tissue Milk Lysozyme Recombinant Protein
2016/5/19
Milk lysozyme is the ubiquitous enzyme in milk of mammals. In this study, the cDNA sequence of a new chicken-type (c-type) milk lysozyme gene (YML), was cloned from yak mammary gland tissue. A 444 bp ...
Regulation of the p53 tumor suppressor gene in the mammary gland and its role in tumorigenesis
Biological sciences p53 Tumor suppressor Mammary gland Tumorigenesis
2015/1/28
Breast cancer is the most frequent tumor type among women. Heightened susceptibility of the breast to tumor development has been associated with early menarche, nulliparity, exposures to ionizing radi...
Leukocytes in bovine virgin mammary gland: flow cytometry imaging during development and resolution of induced influx
bovine virgin mammary gland induced influx
2015/1/20
Distribution of leukocyte types present in virgin bovine mammary glands was analysed in dot plots obtained by flow cytometry (FACS) of samples collected from 10 non-pregnant heifers after induction of...
Regulation of CRBP1 In Mammary Epithelial Cells
CRBP1 parity induced protection breast cancer
2014/12/12
Breast cancer is the second leading cause of death of women in the United States, warranting further investigation into preventative therapies. It has been well documented that early pregnancy results...
The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma
Rhodiola crenulata highly metastatic murine mammary carcinoma
2014/12/12
The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma.
Alternative splicing of MDM2 during breast tumorigenesis and mammary gland *development
Genes proliferation cell cycle growth abnormal genes oncogenes and tumor suppressor protein and tumor
2014/12/11
The regulation of genes involved in proliferation and cell cycle control plays a critical role in normal development and differentiation. Aberrant expression of genes promoting proliferation (oncogene...
Estrogen and progesterone regulate p53 activity in the mouse mammary epithelium through transforming growth factor beta dependent pathways
P53 protein and tumor formation mammary gland p53 fertility estrogen and progesterone p53 radiation cells DNA damage
2014/12/11
Proper regulation of the p53 protein plays a critical role in suppressing tumor formation in a variety of tissues including the mammary gland. Activity of the p53 pathway is diminished in the mammary ...
Regulation of p53 by Mdm4 and ovarian hormones in mouse mammary glands
P53 protein genome cell cycle DNA cell apoptosis cell growth breast cancer
2014/12/11
p53 protein is considered a major player in maintaining the genomic integrity. It regulates cell cycle, recognizes damaged DNA, and promotes apoptosis of cells that are defective or developmentally pr...
The role of ovarian hormones in p53-mediated resistance to mammary tumorigenesis
Pregnant breast cancer rodents estrogen and progestogen therapy breast cancer the incidence of a disease
2014/12/11
A full term pregnancy reduces breast cancer by up to 50%. In rodents, pregnancy or treatment with estrogen and progesterone to mimic pregnancy reduces mammary tumor incidence. The molecular mechanisms...
The Role Of ERα, ERβ And Phytoestrogens From Soy In P53- Mediated Response To Dna Damage In Mammary Epithelium
Biological sciences Breast cancer Estrogen receptors Mammary tumors p53 Phytoestrogens DNA damage
2014/12/11
Estrogenic compounds can stimulate proliferation of the mammary epithelium, but also potentiate the activity of the p53 tumor suppressor protein. These contradictory activities of estrogenic compounds...