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Infections: The Achilles Heel of Immunosuppression for Renal Transplantation and Immunological Renal Disease Management in the Top End of Northern Australia: Case Reports
Renal Transplant Immunological renal disease Lupus Nephritis
2013/1/31
Improved immunosuppression regimens have led to better survival for patients with renal transplant grafts and patients with immunological renal diseases worldwide. However, this is not the case in the...
The Monitoring Interest of BK Virus Load in Renal Allograft Tunisian Recipients: Prospective Study
BK Virus Renal Transplantation Urine and Plasma Viral Load Allograft Dysfunction
2013/1/31
BK virus (BKV) may cause nephropathy in renal transplant recipients receiving immunosuppressive therapy, resulting in renal dysfunction and, possibly graft loss. However, the positive and negative pre...
Surveillance Renal Allograft Biopsy on Diagnosis of BK Virus Nephropathy in Chinese Renal Transplant Recipients
Renal Transplantation Biopsy BK Virus BK Virus Associated Nephropathy Diagnosis
2013/1/31
Objective: We prospectively investigated 121 renal allograft biopsy specimens performed in our center. Methods: BKVAN was diagnosed by light microscopic examination and a positive immunohistochemistry...
Effects of extracellular chloride ion on epithelial sodium channel (ENaC) in arginine vasotocin (AVT)-stimulated renal epithelial cells
extracellular chloride ion ENaC
2009/12/16
The epithelial Na+ channel (ENaC) contributes to control of blood pressure by reabsorbing Na+ in the cortical collecting duct of the kidney. The luminal Cl- concentration in the duct varies under phys...
Type 2a sodium-phosphate co-transporter serves as a histological predictor of renal dysfunction and tubular apical damage in the kidneys of septic mice
renal dysfunction tubular apical damage
2009/12/16
Acute renal failure (ARF) occurs in septic patients and is histologically characterized by tubular apical damages, including brush border breakdown. Nevertheless, little information is available to id...
Is Stat3 and/or p53 mRNA expression a prognostic marker for renal cell carcinoma?
Stat3 p53 mRNA cell carcinoma
2009/12/16
Signal transducer and activator of transcription (Stat) 3 and p53 integrate upstream signals, and are positive and negative regulators of tumor cell proliferation, respectively. Stat3 and p53 also neg...
Circadian expression of the Na+/H+ exchanger NHE3 in the mouse renal medulla
Circadian expression Na+/H+ exchanger NHE3 mouse renal medulla
2009/5/8
Renal tubular NHE3, the Na+/H+ exchanger, is a critical enzyme for electrolyte and acid-base homeostasis in the kidney. We previously demonstrated that the expression of this gene in the kidney foll...
Enhanced Enzymatic Activity of Yeast-like Fungi Responsible for Onychomycosis in Renal Transplant Recipients
Enhanced Enzymatic Activity Yeast-like Fungi Responsible Onychomycosis
2009/4/20
Background: Renal transplant recipients (RTR) are regarded as a group especially predisposed to onychomycosis. The exact mechanism of increased frequency of onychomycosis in RTR is however not fully...
Increased Prevalence of Glycoprotein IIb/IIIa Leu 33 Pro Polymorphism in End Stage Renal Disease Patients on Hemodialysis
hemodialysis fibrinogen receptor polymorphism glycoprotein platelets CVD
2009/4/14
Traditional atherosclerosis risk factors cannot elucidate the increased prevalence of cardiovascular events in end stage renal disease (ESRD) patients on hemodialysis. A previous study has indicated a...
Localization of oxidative DNA damage after Au injection and effects of Au on Cp in renal kidney
Gold (Au) Copper (Cu) Ceruloplasmin (Cp) 8-hydroxydeoxyguanosine (8-OHdG) Metallotionein (MT)
2009/4/1
The present study was carried out to investigate the effect of gold (Au) injection on copper (Cu) and two types of ceruloplasmin (Cp), total Cp (ID1) and active Cp (ID2), metallothionein (MT) in the s...
Acute Harmful Effects after Single Intravenous Dose of Cadmium Fluoride in Rats(First report)-Lethal dose, severe hepatic damage, renal injury, abnormal serum electrolytes and metabolic acidosis-
cadmium fluoride intravenous injection acute lethal toxicity liver and renal dysfunction
2009/3/16
Acute Harmful Effects after Single Intravenous Dose of Cadmium Fluoride in Rats(First report)-Lethal dose, severe hepatic damage, renal injury, abnormal serum electrolytes and metabolic acidosis.
Repeated regression of pulmonary metastases from renal cell carcinoma after treatment using different interferon-alpha preparations
pulmonary metastases renal cell carcinoma interferon-alpha preparations
2009/3/2
A 49-year-old man with pulmonary metastasis from renal cell carcinoma (RCC) was treated with recombinant IFN-α2b (Intron A®). A complete response was achieved within 4 months and thereafter pers...
Antitumor effects of a combination of interferon-alpha and sorafenib on human renal carcinoma cell lines
interferon-alpha sorafenib human renal carcinoma cell lines
2009/3/2
To support the role of interferon (IFN)-α and sorafenib combination therapy against renal cell carcinoma (RCC), the effects of IFN-α and sorafenib on tumor growth, vascular endothelial growth factor...
Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma
RhoC/ROCK pathway clear cell renal cell carcinoma
2009/3/2
To clarify the role of the Rho small GTP-binding protein (Rho) and its major downstream target, ROCK (Rho-associated serine-threonine protein kinase), in progression of renal cell carcinoma (RCC), w...
Significant association of interleukin 10 receptor mRNA levels with renal cell carcinoma metastasis
mRNA renal cell carcinoma metastasis
2009/3/2
Immunosuppressive cytokine, interleukin 10 (IL-10), is associated with progression of the renal cell carcinoma (RCC). However, the roles of its cell surface receptor, interleukin 10 receptor (IL-10R...