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DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
DNA repair cancer therapeutics
2014/12/12
Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease. However, cancer is a tough opponent in this battle and current treatment...
Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation
Ape1 inhibitor base excision repair biomarkers
2014/12/12
There has been a recent upsurge in the development of small-molecule inhibitors specific to DNA repair proteins or proteins peripherally involved in base excision repair and the DNA damage response. T...